摘要
目的探讨无口腔肿瘤手术及放疗史的患者18F-脱氧葡萄糖(FDG)PET/CT显像时舌部局灶性生理性摄取(FPU)的变异模式及特征。方法回顾性分析2013年1月至2017年12月于山西医科大学第一医院行常规全身PET/CT显像的6233例患者,排除有口腔肿瘤手术及放疗史的患者324例,纳入5909例,其中男3418例,女2491例,年龄2~95(平均58)岁。部分患者进行了张口位状态下的局部PET/CT和诊断剂量CT检查。从FDG摄取增高部位和累及范围的角度分析舌部FPU变异模式及形态特征,并测量最大标准摄取值(SUVmax)。结果常规PET/CT显像检出76例患者[男49例,女27例,年龄40~83(平均64)岁]的76个偶发舌部FPU经口腔医学检查及>6个月的随访确认,舌部FPU的发生率为1.29%(76/5909)。76例患者中41例进行了张口位局部PET/CT和诊断剂量CT检查。舌部FPU变异模式可以归纳为3种类型:Ⅰ型,共68例(1.15%,68/5909),FDG摄取仅涉及中线处舌体前部(靠近舌尖部),为"点状"摄取;Ⅱ型,共5例(0.08%,5/5909),FDG摄取主要涉及颏舌肌的中间部分,为"短条形"摄取;Ⅲ型,共3例(0.05%,3/5909),FDG摄取涉及舌体大部及颏舌肌,为"T形"摄取。Ⅰ型、Ⅱ型舌部FPU的SUVmax分别为5.53(4.53,7.30)、19.50(17.10,22.74),3例Ⅲ型SUVmax分别为23.34、27.50和35.14。结论在无口腔疾患手术及放疗史的患者中,舌部FPU有其特定模式和特征,张口位PET/CT显像有助于显示其详细特征。
Objective To analyze variant patterns and characteristics of focal physiological uptake(FPU)in the tongue on 18F-fluorodeoxyglucose(FDG)PET/CT imaging in patients without a history of oral tumor surgery and radiotherapy.Methods A total of 6233 consecutive patients who underwent routine whole-body PET/CT scan between January 2013 and December 2017 in the First Hospital of Shanxi Medical University were investigated retrospectively,and 324 patients with a history of oral surgery and radiotherapy were excluded,the remaining 5909 patients(3418 males,2491 females,age range:2-95(average:58)years)were enrolled.A part of the patients underwent local PET/CT scan and CT scan with diagnostic dose,covering the oral cavity on mouth-opening position.The morphological characteristics of FPU patterns were analyzed,and the maximum standardized uptake value(SUVmax)was measured.Results Seventy-six FPUs in 76 patients(49 males,27 females,age range:40-83(average 64)years)identified by routine whole-body PET/CT scan were confirmed by clinical examination from a specialist in stomatology or follow-up for more than 6 months.Forty-one of the 76 patients subsequently underwent local PET/CT scan and diagnostic CT scan on mouth-opening position.The incidence of FPU in the tongue was 1.29%(76/5909).The FPU patterns could be classified into three types:typeⅠwith FDG uptake involved only anterior part of the tongue body in the midline(near the tip of the tongue),which showed as a"dotted"shape(n=68;1.15%,68/5909);typeⅡwith FDG uptake involved mainly middle part of the genioglossus muscle,which showed as a"bar-shorted"shape(n=5;0.08%,5/5909);typeⅢwith FDG uptake involved large part of the tongue body and the genioglossus,which showed as a"T"shape(n=3;0.05%,3/5909).The SUVmax in patients with typeⅠand typeⅡwere 5.53(4.53,7.30),19.50(17.10,22.74)respectively.The SUVmax in 3 patients with typeⅢwere 23.34,27.50 and 35.14,respectively.Conclusion In patients without a history of oral tumor surgery and radiotherapy,the FPU in the tongue has its specific pattern,and PET/CT scan on mouth-opening position helps to reveal the detailed features.
作者
郝新忠
武志芳
鄢敏
秦志星
程鹏亮
武萍
刘建中
Hao Xinzhong;Wu Zhifang;Yan Min;Qin Zhixing;Cheng Pengliang;Wu Ping;Liu Jianzhong(Department of Nuclear Medicine,the First Hospital of Shanxi Medical University,Taiyuan 030001,China)
出处
《中华核医学与分子影像杂志》
CAS
北大核心
2020年第7期415-420,共6页
Chinese Journal of Nuclear Medicine and Molecular Imaging
