摘要
目的观察抗抑郁药物对脑卒中后抑郁患者的疗效及对治疗依从性的影响。方法选取2017年8月~2019年8月我院收治的60例脑卒中后抑郁症患者作为研究对象,其中30例行常规治疗作为对照组,30例行抗抑郁药物治疗作为观察组,比较两组患者治疗效果。结果两组间HAMD、NIHSS评分比较,治疗前无差异,治疗后观察组两项评分明显低于对照组(P<0.05);两组患者治疗后均的血清因子水平均有改善,但从改善程度来看观察组优于对照组(P<0.05);患者治疗依从性比较观察组VS对照组为93.3%VS70.0%,差异有统计学意义(P<0.05)。结论抗抑郁药物能够改善脑卒中后抑郁患者的抑郁情绪和神经功能缺损,还能够提升患者治疗依从性。
Objective To observe the effect and compliance of antidepressants in the treatment of post-stroke depression.Methods 60 patients with post-stroke depression admitted to our hospital from August 2017 to August 2019 were selected as the subjects of study,30 of them were treated with routine therapy as the control group,30 of them were treated with antidepressants as the observation group,and the therapeutic effects of the two groups were compared.Results There was no difference in HAMD and NIHSS scores between the two groups before treatment.After treatment,the improvement in the observation group were better than those in control group(P<0.05).The level of serum factors in both of two groups improved after treatment,but the improvement the observation group was better that in the observation group(P<0.05).Patients'treatment compliance in the observation group was higher than that in the control group(P<0.05).Conclusion Antidepressant treatment of post-stroke patients with depression has a significant effect on the improvement of depression and neurological deficit,which can improve the treatment compliance of patients.
作者
田智斌
赵掌权
王战英
边莹
TIAN Zhibin;ZHAO Zhangquan;WANG Zhanying(The Xianyang Hospital of Yanan University,Xianyang 712000,China)
出处
《国际精神病学杂志》
2020年第3期533-535,共3页
Journal Of International Psychiatry
