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肾移植术后早期一过性精神异常的回顾性分析

Clinical diagnosis and treatment of transient psychosis disorder in patients after kidney transplantation
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摘要 目的回顾性分析肾移植术后早期一过性精神异常的诊治。方法回顾性分析2017年11月~2019年11月我院肾移植术后出现早期一过性精神异常的97例患者的临床资料。结果97例患者用药后其精神症状均逐渐消失,期间出现嗜睡状态54例(55.7%),呼吸伴鼾声且生命平稳体征者41例(42.3%)。24~48h后依据患者的实际病情将镇静药物剂量逐渐减少到停用,均没有精神症状再次出现。14~45d后痊愈出院97例。地西泮治疗无效者2例(2.1%),改用丙泊酚治疗24h后症状均消失。3~27个月的随访发现:患者血肌酐水平63.1~205.7μmol/L,平均(98.4±10.3)μmol/L,均再没有精神症状。结论肾移植术后早期部分患者出现一过性精神异常,治疗后预后好。 Objective To analyze the clinical diagnosis and treatment of early transient psychosis in patients after renal transplantation.Methods The clinical data of 97 cases of patients with transient psychosis after kidney transplantation from November 2017 to November 2019 were analyzed retrospectively.Results After treatment,the mental symptoms in all of the 97 patients gradually disappeared;54 patients(55.7%)were drowsy during the treatment,41 patients(42.3%)had snoring with stable vital signs.After 24-48 hours of treatment,the sedative dosage for all the patients was gradually reduced and stop according to the actual condition of the patients,and there was no mental symptoms again.All of the 97 cases(100%)were cured and discharged after 14-45 days.Two patients(2.1%)had no effect by diazepam treatment.The patients were followed up for 3-27 months.The serum creatinine level of the patients was 63.1-205.7μmol/L,with an average of(98.4±10.3)μmol/L.all of them had no mental symptoms appeared again.Conclusion Part of patients after kidney transplantation will have transient psychosis disorder,which can be effectively treated.
作者 熊烈 丁寿宁 杨铁 杨爱桃 XIONG Lie;DING Shouning;YANG Tie(Yiyang Central Hospital,Yiyang 413000,China)
出处 《国际精神病学杂志》 2020年第3期514-516,526,共4页 Journal Of International Psychiatry
关键词 肾移植 术后早期 一过性精神异常 临床诊治 Kidney transplantation Early postoperative period Transient psychosis disorder Clinical diagnosis and treatment
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