摘要
目的探讨青春期多囊卵巢综合征(PCOS)患者的中医证型分布及证型间临床指标的差异性。方法收集2015年1月~2019年9月黑龙江中医药大学附属第一医院妇科门诊临床科研信息一体化系统中诊断为青春期PCOS患者266例,分别为脾虚痰湿证65例,痰瘀互结证73例,肾虚肝郁证82例,肾虚血瘀证46例,分析比较4组间临床生化各项指标的差异。结果脾虚痰湿证、痰瘀互结证患者的体重、BMI、WC、HC显著高于肾虚血瘀证、肾虚肝郁证(P<0.05);痰瘀互结证患者的WHR显著高于肾虚血瘀证、肾虚肝郁证(P<0.05)。脾虚痰湿证、痰瘀互结证患者的SHBG显著低于肾虚血瘀证、肾虚肝郁证(P<0.05);痰瘀互结证患者的FAI显著高于肾虚肝郁证(P<0.05)。痰瘀互结证患者FINS、HOMA-IR及IR发生率显著高于肾虚血瘀证、肾虚肝郁证(P<0.05)。脾虚痰湿证、痰瘀互结证患者的LAP显著高于肾虚血瘀证、肾虚肝郁证(P<0.05)。结论不同证型青春期PCOS患者临床体征及生化指标存在差异,临床诊治过程中应将辨证与辨病充分相结合,以取得更好的临床疗效。
Objective To explore the distribution of TCM syndrome types and the differences in clinical indicators between syndrome types in patients with adolescent polycystic ovary syndrome(PCOS).Methods From January 2015 to September 2019,a total of 266 patients diagnosed with adolescent PCOS were collected from the integrated clinical research information system of the gynecology clinic of the First Affiliated Hospital of Heilongjiang University of Chinese Medicine.There were 65 cases of spleen deficiency and phlegm dampness syndrome,73 cases of stagnation of phlegm and stasis syndrome,82 cases of kidney deficiency and liver stagnation syndrome,and 46 cases of kidney deficiency and blood stasis syndrome.The differences in clinical biochemical indicators between the four groups were analyzed and compared.Results The weight,BMI,WC,and HC of patients with spleen deficiency and phlegm dampness syndrome and stagnation of phlegm and stasis syndrome were significantly higher than those of kidney deficiency and blood stasis syndrome and kidney deficiency and liver stagnation syndrome(P<0.05).The WHR of patients with stagnation of phlegm and stasis syndrome was significantly higher than that of kidney deficiency and blood stasis syndrome and kidney deficiency and liver stagnation syndrome(P<0.05).The SHBG level in patients with spleen deficiency and phlegm dampness syndrome and stagnation of phlegm and stasis syndrome was significantly lower than that in kidney deficiency blood stasis syndrome and kidney deficiency liver stagnation syndrome(P<0.05).The FAI in patients with stagnation of phlegm and stasis syndrome was significantly higher than that in kidney deficiency and liver stagnation syndrome(P<0.05).The FINS,HOMA-IR and incidence of IR of patients with stagnation of phlegm and stasis syndrome were significantly higher than those of kidney deficiency and blood stasis syndrome and kidney deficiency and liver stagnation syndrome(P<0.05).The LAP in patients with spleen deficiency and phlegm dampness syndrome and stagnation of phlegm and stasis syndrome was significantly higher than that in kidney deficiency and blood stasis syndrome and kidney deficiency and liver stagnation syndromes(P<0.05).Conclusion There are differences in clinical signs and biochemical indicators of adolescent PCOS patients with different syndrome types.In the process of clinical diagnosis and treatment,syndrome differentiation and disease differentiation should be fully combined to achieve better clinical efficacy.
作者
杨艳婷
侯丽辉
王颖
Yang Yanting;Hou Lihui;Wang Ying(Heilongjiang University of Chinese Medicine,Heilongjiang 150040,China)
出处
《医学研究杂志》
2020年第7期68-72,81,共6页
Journal of Medical Research
基金
国家自然科学基金青年科学基金资助项目(81904235)
国家中医药管理局全国名老中医药专家传承工作室建设项目(2014-9-10)
黑龙江省普通高等学校青年创新人才培养计划项目(UNPYSCT-2018227)。
关键词
青春期
多囊卵巢综合征
证型
临床分析
Adolescent
Polycystic ovary syndrome
Syndromes
Clinical analysis
