摘要
目的研究硝苯地平联合硫酸镁治疗妊娠高血压疾病的临床价值。方法纳入2018年3月-2019年2月收治的102例妊娠高血压疾病患者,按照随机数字表法分为2组。对照组51例予以硫酸镁单药治疗,观察组51例采用硝苯地平、硫酸镁联合治疗,对比2组的血液流变学指标、血压水平、妊娠结局。结果观察组患者治疗后的红细胞压积、血浆黏度、全血低切黏度、全血高切黏度以及收缩压、舒张压水平均明显低于对照组,不良妊娠结局发生率亦低于对照组,差异具有统计学意义(P<0.05)。结论对妊娠高血压疾病患者应用硝苯地平联合硫酸镁治疗不仅能够改善血液流变学,还可提高血压控制效果,优化妊娠结局。
Objective To study the clinical value of nifedipine combined with magnesium sulfate in the treatment of pregnancy induced hypertension.Methods 102 patients with pregnancy induced hypertension admitted from March 2018 to February 2019 were included in the study.They were divided into two groups according to the random number table method.51 cases in the control group were treated with magnesium sulfate alone,and 51 cases in the observation group were treated with nifedipine and magnesium sulfate in combination.The blood flow index,blood pressure level and pregnancy outcome of the two groups were compared.Results the mean of hematocrit,plasma viscosity,whole blood low shear viscosity,whole blood high shear viscosity,systolic blood pressure and diastolic blood pressure in the observation group were significantly lower than those in the control group,and the incidence of adverse pregnancy outcome was also lower than that in the control group(P<0.05).Conclusion nifedipine combined with magnesium sulfate can not only improve the blood flow,but also improve the effect of blood pressure control and optimize the outcome of pregnancy.
作者
陈思洁
苏燕红
洪淑蓉
连淑萍
Chen Sijie;Su Yanhong;Hong Shurong(The Longwen Branch of Zhangzhou Hospital,Zhangzhou,Fujian 363000)
出处
《基层医学论坛》
2020年第19期2683-2685,共3页
The Medical Forum
关键词
妊娠高血压疾病
硝苯地平
硫酸镁
联合治疗
临床价值
Pregnancy induced hypertension
Nifedipine
Magnesium sulfate
United treatment
Clinical value