摘要
目的探讨艾滋病(AIDS)并发肺结核感染的危险因素。方法选取2015年1月~2019年11月广西壮族自治区桂林市第三人民医院收治的3224例AIDS患者作为研究对象,根据有无并发肺结核感染分为感染组(255例)与非感染组(2969例)。比较两组基本资料和病情相关情况。采用多因素logistic回归分析AIDS合并肺结核感染的相关因素。结果感染组中有吸烟史、家庭收入低、无业、静脉吸毒等患者比例显著高于非感染组(P <0.05),而卡介苗接种史患者显著低于非感染组(P <0.05)。两组年龄、性别、饮酒史、教育程度、婚姻状况和城乡分布等资料比较差异无统计学意义(P> 0.05)。多因素logistic回归分析发现吸烟史、无业、静脉吸毒是导致AIDS合并肺结核感染的独立危险因素(P <0.05),卡介苗接种史是AIDS合并肺结核感染的保护因素(P <0.05)。结论家庭低收入、无业、静脉吸毒、有吸烟史是AIDS患者发生肺结核的独立危险因素,而接种卡介苗是AIDS患者发生肺结核保护因素。
Objective To explore the risk factors of acquired immunodeficiency syndrome(AIDS)complicated with tuberculosis infection.Methods A total of 3224 AIDS patients admitted to Guilin Third People′s Hospital of Cuangxi Zhuang Autonomous Region from January 2015 to November 2019 were selected as the subjects.According to the presence or absence of tuberculosis infection,they were divided into infection group(255 cases)and non infection group(2969 cases).The basic data and disease-related conditions were compared between the two groups.The risk factors of AIDS complicated with tuberculosis infection were analysed by multivariate related factors.Results The proportion of patients with smoking history,low family income,unemployment and intravenous drug use in the infection group were significantly higher than those in the non infection group(P<0.05),while the proportion of patients with BCG vaccination history were significantly lower than that in the non infection group(P<0.05).There were no significant differences between the two groups in age,gender,drinking history,education level,marital status,urban and rural distribution(P>0.05).Multivariate logistic regression analysis showed that smoking history,unemployment,intravenous drug use were the independent risk factors of AIDS complicated with tuberculosis infection(P<0.05),and BCG vaccination history was the protective factor of AIDS with tuberculosis infection(P<0.05).Conclusion Low family income,unemployment,intravenous drug use,smoking history are the independent risk factors of AIDS with tuberculosis infection,while BCG vaccination is the protective factor of AIDS with tuberculosis infection.
作者
徐玉萍
田群
王继业
XU Yuping;TIAN Qun;WANG Jiye(Health Center of Guilin Medical College,Guangxi Zhuang Autonomous Region,Guilin 541004,China;Infectious Disease Department,Guilin Third People's Hospital,Guangxi Zhuang Autonomous Region,Guilin 541001,China;Department of Respiratory and Critical Medicine,the Second People's Hospital of Guilin,Guangxi Zhuang Autonomous Region,Guilin 541001,China)
出处
《中国医药导报》
CAS
2020年第17期145-148,共4页
China Medical Herald
基金
广西医药卫生自筹经费计划课题项目(Z2014291)。
关键词
艾滋病
肺结核
感染
危险因素
Acquired immunodeficiency syndrome
Tuberculosis
Infection
Risk factors
