脑梗死急性期末患者神经功能缺损程度影响因素的多元回归分析被引量：7

Multiple regression analysis of the influencing factors of acute terminal neurological deficit in patients with cerebral infarction

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摘要目的分析脑梗死急性期末患者与神经功能缺损程度的影响因素。方法回顾性分析2015年8月~2016年8月海南省第三人民医院神经内科收治68例急性期脑梗死患者。收集患者一般资料、颅内压、脑灌注压、梗死灶体积、实验室指标、既往史评分及起病至入院时间等,分析各指标与神经功能缺损评分(NFDS)的相关性。结果急性期脑梗死患者颅内压、病灶体积、总胆固醇、三酰甘油、纤维蛋白原、既往史评分及起病至入院时间与NFDS评分呈正相关(rs> 0,P <0.05)。病灶体积、起病至入院时间和总胆固醇是NFDS评分的影响因素(P <0.05)。结论病灶体积、总胆固醇和起病至入院时间等因素与脑梗死急性期末患者的预后具有相关性,准确把握相关影响因素和及时干预对改善患者神经功缺损能至关重要。 Objective To analyze the influencing factors of patients with acute cerebral infarction and the degree of neurological deficits.Methods A retrospective analysis was performed on 68 patients with acute cerebral infarction admitted to the Department of Neurology,the Third People′s Hospital of Hainan from August 2015 to August 2016.The general data,intracranial pressure,cerebral perfusion pressure,infarct volume,laboratory index,previous history score and time from onset to admission of all patients were collected,and the correlation between each index and the neurological functional deficit scale(NFDS)score were analyzed.Results In patients with acute cerebral infarction,the levels of intracranial pressure,lesion volume,total cholesterol,triacylglycerol,fibrinogen,past history score,and time from onset to admission were positively correlated with NFDS score(rs>0,P<0.05).The size of the lesion,the time from onset to admission,and total cholesterol were influencing factors for the NFDS score(P<0.05).Conclusion Factors such as lesion volume,total cholesterol,and the time from onset to admission are related to the prognosis of patients with cerebral infarction at the end of the acute phase.Accurately grasping the relevant influencing factors and timely intervention are essential to improve the patients′neurological deficit.

作者李华坚陈海云何超明林敏庞明武高唯一 LI Huajian;CHEN Haiyun;HE Chaoming;LIN Min;PANG Mingwu;GAO Weiyi(Department of Neurology,the Third People's Hospital of Hainan,Hainan Province,Haikou 572000,China)

机构地区海南省第三人民医院神经内科

出处《中国医药导报》 CAS 2020年第17期84-86,90,共4页 China Medical Herald

基金海南省卫生计生行业科研项目(18A200030)。

关键词脑梗死神经功能缺损影响因素多元回归分析神经功能缺损程度评分 Cerebral infarction Neurological deficits Influencing factors Multiple regression analysis Neurological functional deficit scale

分类号 R743 [医药卫生—神经病学与精神病学]