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喷他佐辛与舒芬太尼抑制瑞芬太尼麻醉后痛觉过敏的效果比较 被引量:4

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摘要 目的比较喷他佐辛与舒芬太尼抑制瑞芬太尼麻醉后痛觉过敏的临床效果。方法选取2018年6月-2019年6月娄底市中心医院收治的ASAⅠ~Ⅱ级择期行妇科腹腔镜手术的患者80例,根据治疗方式不同分为观察组和对照组,每组40例。手术完成前10 min,观察组选择喷他佐辛进行静脉注射,对照组选择舒芬太尼进行静脉注射。比较2组苏醒及拔管时间、Ramsay镇静评分及疼痛评分、拔管后不良反应发生情况。结果2组苏醒及拔管时间比较差异无统计学意义(P>0.05);观察组拔管时及拔管后4 h Ramsay镇静评分和疼痛评分均低于对照组(P<0.05);观察组不良反应发生率为7.50%,低于对照组的25.00%(χ~2=4.501,P<0.05)。结论对于ASAⅠ~Ⅱ级选择择期行妇科腹腔镜手术患者,应用喷他佐辛的舒适性和安全性更高,可有效抑制瑞芬太尼麻醉后痛觉过敏,值得临床推广应用。
作者 叶琴
出处 《临床合理用药杂志》 2020年第14期58-59,共2页 Chinese Journal of Clinical Rational Drug Use
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