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以复视为主要症状的眼肌麻痹病因分析 被引量:8

Analysis of etiology of ophthalmoplegia as a main symptom
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摘要 目的研究以复视为主要症状的眼肌麻痹常见病因。方法收集我院神经内科2012年7月~2017年12月124例眼肌麻痹患者临床资料进行回顾性分析。结果124例患者平均年龄为(61.60±14.23)岁,病因明确15种,常见病因是2型糖尿病28例,糖耐量异常7例,痛性眼肌麻痹28例,重症肌无力13例,脑梗死7例,鼻咽癌5例,副瘤综合征3例,结核性脑膜炎1例,硬脑膜动静脉瘘1例,动脉瘤3例,病毒感染2例,垂体瘤放疗后神经损伤1例,Wernike脑病2例,吉兰-巴雷综合征3例,外伤1例,未明确病因19例。结论以复视为主要症状的眼肌麻痹病因多种多样,早期临床表现缺乏特异性,容易误诊,眼科或神经科医生要提高警惕,其中糖尿病相关性眼肌麻痹为最常见原因。 Objective To study the common etiology of ophthalmoplegia as a major symptom.Methods The clinical data of 124 patients with ophthalmoplegia from July 2012 to December 2017 in our Department of Neurology were retrospectively analyzed.Results The average age of 124 patients was(61.60±14.23)years old,and there were 15 causes of clear etiology.There were 28 cases of type 2 diabetes,7 cases of impaired glucose tolerance,28 cases of painful ophthalmoplegia,13 cases of myasthenia gravis,and 7 cases of cerebral infarction,5 cases of nasopharyngeal carcinoma,3 cases of paraneoplastic syndrome,1 case of tuberculous meningitis,1 case of dural arteriovenous fistula,3 cases of aneurysm,2 cases of viral infection,1 case of nerve injury after radiotherapy of pituitary tumor,2 cases of Wernike encephalopathy,3 cases of Guillain-Barrésyndrome,1 case of trauma,and 19 cases of unclear cause.Conclusion The etiology of ophthalmoplegia as the main symptom is diverse.The early clinical manifestations are lack of specificity and are easily misdiagnosed.Ophthalmology or neurologists should be vigilant.Among them,diabetes-related ophthalmoplegia is the most common cause.
作者 常现超 俞虎 严旺 洪文轲 CHANG Xianchao;YU Hu;YAN Wang;HONG Wenke(Department of Neurology,Hwa Mei Hospital,University of Chinese Academy of Sciences,Ningbo 315010,China)
出处 《中国现代医生》 2020年第12期106-109,共4页 China Modern Doctor
基金 浙江省自然科学基金资助项目(LY19H090002)。
关键词 眼肌麻痹 复视 糖尿病 病因 Ophthalmoplegia Diplopia Diabetes Etiology
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