摘要
目的探讨右美托咪定在高龄患者围术期的麻醉效果。方法选取2018年1月~2019年11月间我院收冶的腹腔镜胃癌根治术患者100例作为研究对象,按随机数字表法分为对照组和实验组,每组50例,对照组围术期执行异丙酚联合七氟烷镇痛支持,实验组围术期执行右美托咪定联合七氟烷镇痛支持,观察两组平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO2)、脑电双频指数(BIS)、术后苏醒时间、拔管时间及不良反应差异。结果两组气管内插管前即刻(T2)至术后0.5 h(T5)患者MAP、HR、BIS低于麻醉诱导前(T1),实验组不良反应发生率(4.0%)低于对照组(14.0%),差异均有统计学意义(P<0.05)。结论高龄患者手术治疗中实行右美托咪定麻醉方案,可保障较佳的血流动力学稳定性,降低围术期风险事件发生率。
Objective To explore the anesthetic effect of dexmedetomidine in perioperative period of elderly patients.Methods One hundred patients given laparoscopic radical gastrectomy in our hospital from January 2018 to November 2019 were selected as research subjects,and were divided into the control group(n=50)and the research group(n=50)by the random number table.Propofol combined with sevoflurane analgesia support treatment was given to the control group in perioperative period;dexmedetomidine combined with sevoflurane analgesia support treatment was given to the research group in perioperative period.The differences of mean arterial pressure(MAP),heart rate(HR),oxygen saturation of blood(SpO2),bispectral index(BIS),postoperative recovery time,extubation time and adverse reactions in the two groups were observed.Results The MAP,HR,RIS of patients from immediately before endotracheal intubation(T2)to postoperative 0.5 hour(T5)was lower than that before anesthesia induction(T1)in two groups;the incidence of adverse reactions(4.0%)in the research group was lower than that in the control group(14.0%),all with statistically significant differences(P<0.05).Conclusion The anesthesia scheme using dexmedetomidine in surgical treatment for elderly patients can guarantee better hemodynamic stability and reduce the incidence of perioperative risk events.
作者
刘翠翠
李林林
LIU Cuicui;LI Linlin(Department of Anesthesiology,the Affiliated Hospital of Qingdao University,Qingdao 266003,China)
出处
《中国现代医生》
2020年第11期139-141,145,共4页
China Modern Doctor
关键词
高龄
右美托咪定
麻醉
镇痛
Elderly
Dexmedetomidine
Anesthesia
Analgesia
