摘要
目的探讨丙美卡因复合氢吗啡酮对七氟醚全麻斜视手术患儿苏醒期躁动的安全性和有效性。方法选取枣庄市妇幼保健院麻醉科2018年6月~2019年5月七氟醚全麻下斜视矫正术的患儿120例,按照随机数字表法分为两组:丙美卡因组(Ⅰ组)60例,麻醉诱导后应用丙美卡因;丙美卡因复合氢吗啡酮组(Ⅱ组)60例,麻醉诱导后给予丙美卡因和氢吗啡酮。比较两组麻醉时间、手术时间、清醒时间、拔除喉罩时间、出PACU时间、苏醒期躁动评分、躁动发生率、恶心呕吐、低氧、呛咳、嗜睡等发生情况。结果Ⅱ组麻醉时间、手术时间、清醒时间、拔除喉罩管时间、出PACU时间与Ⅰ组比较,差异无统计学意义(P>0.05)。Ⅱ组苏醒期躁动评分及躁动发生率均低于Ⅰ组,差异有统计学意义(P<0.05);Ⅱ组麻醉苏醒期呛咳不良反应发生率低于Ⅰ组,差异有统计学意义(P<0.05);Ⅱ组恶心呕吐、低氧、嗜睡等不良反应发生情况与Ⅰ组比较,差异无统计学意义(P>0.05)。结论丙美卡因复合氢吗啡酮用于七氟醚全麻斜视手术患儿可明显有效降低苏醒期躁动评分及躁动发生率,安全性好,值得临床进一步推广。
Objective To explore the safety and effectiveness of promecaine combined with hydromorphone on emergence agitation in children with strabismus surgery under sevoflurane general anesthesia.Methods 120 children with strabismus correction under sevoflurane general anesthesia were selected from June 2018 to May 2019 in Zaozhuang Maternal and Child Health Hospital.They were divided into two groups according to the random number table method.60 patients in the propantheline group(group I)were treated with propantheline after induction of anesthesia.60 patients in the propantheline combined with hydromorphone group(group II)were given propantheline and hydromorphone after induction of anesthesia.The anesthesia time,operation,awake time,time to remove the laryngeal mask tube,our of the PVCU time,emergence agitation scores,incidence of agitation,nausea and vomiting,hypoxia,cough,and lethargy were compared between the two groups.Results There was no significant difference in anesthesia time,operation time,awake time,time to remove the laryngeal mask tube,and out of the PACU time between groupⅡand groupⅠ(P>0.05).The agitation score and the incidence of agitation in groupⅡwere lower than those in groupⅠduring waking up period,and the difference was statistically significant(P<0.05).The incidence of poor cough reflex in the groupⅡwas lower than that in groupⅠduring wake-up period of anesthesia,and the difference was statistically significant(P<0.05).There was no significantly difference in the incidence of adverse reactions such as nausea,vomiting,hypoxia and drowsiness between groupⅡand groupⅠ(P>0.05).Conclusion Propantheline combined with hydromorphone for strabismus surgery under sevoflurane general anesthesia can significantly reduce the emergence agitation score and the incidence of agitation.It is safe and worthy of further clinical promotion.
作者
王建
郑伟
WANG Jian;ZHENG Wei(Department of Anesthesiology,Zaozhuang Maternal and Child Health Hospital in Shandong Province,Zaozhuang 277100,China)
出处
《中国现代医生》
2020年第11期131-134,共4页
China Modern Doctor
关键词
丙美卡因
氢吗啡酮
七氟醚
苏醒期躁动
术后并发症
Propantheline
Hydromorphone
Sevoflurane
Emergence agitation
Postoperative complications
