摘要
古代经典名方研发过程中,处方药材的“遵古”炮制研究尤为重要,将处方药材炮制成与古代医籍原方记载保持一致,且符合现代应用标准的饮片,是经典名方研发工作的重要环节。本文以经典名方“升陷汤”中桔梗药材的炮制为例,对桔梗净制、水处理、切制及干燥工艺进行研究,须经过确立并验证炮制方法与工艺、工艺放大试验、中试生产等环节,考虑药材—饮片—标准煎液的相关性,最终确定药材质量标准。
In the process of research and development of ancient famous classical formulas,the processing of following original methods of prescription materials is particularly important.To make prescription medicines in conformity with the origin records of ancient medical books,and pieces that meet the modern application standards,it is an important link in the research and development of ancient famous classical formulas.This paper takes the processing research of platycodon grandiflorum in Shengxian decoction as an example,studies the technology of Platycodon grandiflorum purification,water treatment,cutting and drying,establishes and verifies the processing method and technology,process scale-up test,pilot production and other links,and finally determines the quality standard of the medicinal materials by considering the correlation of medicinal materials-pieces-standard decoction.
作者
王野
邢春来
苏文龙
张洪涛
张啸环
WANG Ye;XING Chunlai;SU Wenlong;ZHANG Hongtao;ZHANG Xiaohuan(Changchun University of Chinese Medicine,Changchun 130117,China)
出处
《吉林中医药》
2020年第5期671-674,共4页
Jilin Journal of Chinese Medicine
基金
吉林省科学技术厅重点研发项目(20190304077YY)。
关键词
桔梗
炮制
研究方法
platycodon grandifl orum
processing
research methods
