摘要
目的探讨牵引辅助下胃镜胃空肠吻合术的可行性及安全性。方法将实验猪3只,随机分为非存活组(1只)和存活组(2只),均进行牙线外牵引辅助下胃镜胃空肠吻合术。非存活组术毕尸解亚甲蓝测漏;存活组术后第3天进流食,1周后复查胃镜并尸解评估腹腔感染以及吻合口组织学形成情况。结果3只实验猪手术均获成功,手术时间24~41 min。非存活组术毕尸解亚甲蓝测漏阴性。存活组术后状态良好,术后1周尸解观察腹腔无脏器损伤及感染征象,病理见吻合口部位大量纤维组织增生,连接紧密,并有炎症细胞浸润。结论牙线外牵引辅助下胃镜胃空肠吻合术安全可行,值得进一步研究完善。
Objective To investigate the feasibility and safety of gastroscopic gastrojejunostomy assisted by traction.Methods Three experimental pigs were randomly divided into non-survival group(1 pig)and survival group(2 pigs),and all underwent gastroscopic gastrojejunostomy assisted by dental floss external traction.Methylene blue leak detection was conducted in the non-survival group after postoperative autopsy,while pigs in the survival group had fluids on the third day after operation,and gastroscopic review was carried out one week later and autopsy was performed to evaluate the status of abdominal infection and histological formation of anastomosis site.Results All three experimental pigs were successfully operated,with an operation duration of 24 to 41 minutes.Methylene blue leak detection was found to be negative in the non-survival group.Pigs in the survival group presented good postoperative condition.There were no signs of abdominal organ injury or infection at autopsy one week after operation.Histopathology revealed a large amount of fibrous tissue hyperplasia at anastomosis site,with tight connections and infiltration of inflammatory cells.Conclusion Gastroscopic gastrojejunostomy assisted by dental floss external traction is safe and feasible,which is worthy of further study and improvement.
作者
许佳祥
方植力
白俊杰
罗犇
卓锦辉
范晓玲
董芳芬
施宏
XU Jiaxiang;FANG Zhili;BAI Junjie;LUO Ben;ZHUO Jinhui;FAN Xiaoling;DONG Fangfen;SHI Hong(Department of Clinical Medicine,Fujian Medical University,Fuzhou 350122,China;Fujian Medical University Union Hospital,Fuzhou 350001,China;Fujian Medical University Cancer Hospital,Fujian Cancer Hospital,Fuzhou 350014,China)
出处
《微创医学》
2020年第2期138-141,共4页
Journal of Minimally Invasive Medicine
基金
福建医科大学大学生创新创业训练计划资助项目(编号:201803)。
关键词
胃镜
胃空肠吻合术
牙线牵引
动物实验
Gastroscopy
Gastrojejunostomy
Dental floss traction
Animal experiment
