期刊文献+

医疗大数据应用于真实世界研究现状及展望 被引量:14

Status and Prospect of Medical Big Data Applied to Real World Study
暂未订购
导出
摘要 基于文献调研,分析医疗大数据应用于真实世界研究的开展情况,阐述大数据时代真实世界研究优势,包括外部真实性高、目标人群广泛、证据整体性强、获取证据高效等方面,提出医疗大数据应用于真实世界研究在基础架构和具体开展两方面面临的挑战。 The paper analyzes the development of medical big data applied to real world study based on literature research,expounds on the advantages of real world study in the era of big data,including high external authenticity,broad target population,strong evidence integrity,efficient evidence acquisition,etc.,proposes the challenges of applying medical big data to real world study in terms of infrastructure and concrete development.
作者 刘爽 冯时 郭昊 卢瑗瑗 弓孟春 吴开春 LIU Shuang;FENG Shi;GUO Hao;LU Yuanyuan;GONG Mengchun;WU Kaichun(Chinese Academy of Medical Sciences,Peking Union Medical College Hospital,Beijing 100730,China;Digital China Health Technologies Co.,Ltd.,Beijing 100020,China;Air Force Medical University,Xijing Hospital,National Clinical Research Center for Digestive Diseases,Xi′an 710032,China;Center of Rare Disease,Chinese Academy of Medical Sciences,Beijing 100730,China)
出处 《医学信息学杂志》 CAS 2020年第3期14-18,共5页 Journal of Medical Informatics
基金 国家自然科学基金资助项目“消化系肿瘤发生发展的关键分子事件及其临床意义”(项目编号:81421003),“消化道肿瘤”(项目编号:81822031) 国家重点研发计划“规范化大型胃癌队列的建立及其可用性研究”(项目编号:2017YFC0908300)。
关键词 大数据 医疗 真实世界研究 big data medical real world study
  • 相关文献

参考文献2

二级参考文献31

  • 1Vicini P, Fields 0, Lai E, et al. Precision Medicine in the Agesequencing in drug discovery and development [J]. ClinicalPharmacology and Therapeutics, 2016,(99) : 198 -207.
  • 2Collins FS, Varmus H. A New Initiative on Precision Medi-cine [J]. The New England Journal of Medicine, 2015,(372) : 793 -795.
  • 3Baro E, Degoul S, Beuscart R, et al. Toward a Literature -Driven Definition of Big Data in Healthcare [ J ]. BioMedResearch International, 2015,(2015) : 639021.
  • 4Hochster HS, Niedzwiecki D. Big Data,Small Effects [J].Journal of Clinical Oncology : Official Journal of the Ameri-can Society of Clinical Oncology 2016 ; pii : JC0658161.[Epub ahead of print ].
  • 5Papolos A, Narula J,Bavishi C, et al. U. S. Hospital Useof Echocardiography : insights from the nationwide inpatientsample [ J]. Journal of the American College of Cardiology,2016, (67) : 502-511.
  • 6Minikel EV, Vallabh SM,Lek M,et al. Quantifying Priondisease Penetrance Using Large Population Control Cohorts[J]. Science Translational Medicine, 2016, (8) : 322ra9.
  • 7Yan X,Chu JH, Gomez J, et al. Noninvasive Analysis ofthe Sputum Transcriptome Discriminates Clinical Phenotypesof Asthma. American Journal of Respiratory and CriticalCare Medicine, 2015,(191) : 1116-1125.
  • 8Toga AW, Foster I,Kesselman C, et al. Big BiomedicalData as the Key Resource for Discovery Science [ J ] , Jour-nal of the American Medical Informatics Association, 2015 ,(22) ; 1126-1131.
  • 9Beyer MA DL. The Importance of "Big Data': a definition[EB/OL] .[2015 -01 -10]. http: //wwwgartnercom/it -glossary/big - data/ 2012.
  • 10Dinov ID. Methodological Challenges and Analytic Opportu-nities for Modeling and Interpreting Big Healthcare Data[J]. GigaScience,2016,(5): 12.

共引文献24

同被引文献163

引证文献14

二级引证文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部