摘要
心脏骤停后综合症是心跳骤停患者的常见并发症,也是患者不良预后的主要原因。心跳骤停后的凝血及纤溶功能紊乱是心脏骤停后综合征的主要病理生理机制,继发于此的器官功能障碍导致患者预后不佳。针对此种现象,目前有较多研究对心跳骤停后体内凝血功能变化做出阐述。基于此种病理生理机制,抗凝治疗,溶栓治疗,包括抗血小板治疗对于心跳骤停患者的获益目前尚无定论,值得进一步探讨。本文将从心脏骤停后体内凝血系统的病理变化,凝血功能改变对患者器官功能及预后的影响,抗凝及溶栓治疗的研究进展及争议几方面进行阐述,以期对于心跳骤停患者的治疗提供思路。
Post-cardiac arrest syndrome is a common complication in patients with cardiac arrest and it is also the main reason for the poor prognosis.Disorders of coagulation and fibrinolysis are the main pathophysiological mechanism of post-cardiac arrest syndrome and organ dysfunction secondary to this leads to poor prognosis.In response to this phenomenon there are many studies that explain the changes in coagulation after cardiac arrest.Based on this pathophysiological mechanism the benefits of anticoagulation thrombolysis including antiplatelet therapy for patients with cardiac arrest have not been determined.The aim of this article was to review changes in coagulation after cardiac arrest the impact on organ function and prognosis of patients research and controversy of anticoagulation and thrombolytic therapy.
作者
崔畅
秦宇红
CUI Chang;QIN Yuhong(Department of Emergency,Peking University International Hospital,Beijing 102200 China)
出处
《中国继续医学教育》
2020年第15期103-105,共3页
China Continuing Medical Education
