摘要
目的探讨干眼患者主观症状与临床指标的相关性。方法采用眼表疾病指数(OSDI)评分法对239例(239眼)干眼患者的眼部症状进行问卷调查评分,同时评估患者的角膜荧光素钠染色(FL)评分、泪膜破裂时间(BUT)以及泪液分泌试验(SIT)等,分析干眼症状与临床指标的相关性。结果239例干眼患者ODSI与FL评分、BUT、SIT值及年龄均无相关关系(r=0.044、0.011、0.011及0.048,P>0.05);患者年龄与BUT和SIT值呈负相关(r=-0.154和-0.251,P<0.05),与FL评分呈正相关(r=0.140,P<0.05)。其中,眼干涩与SIT值呈负相关(r=-0.203,P<0.05);视力波动与FL评分呈正相关(r=0.163,P<0.05);分泌物增多与FL评分呈正相关(r=0.139,P<0.05);其他干眼症状与FL、BUT及SIT值均无明显关系(P>0.05)。结论干眼患者的大部分主观症状和客观检查之间的关联性较差,这可能对临床上干眼的诊断和治疗产生一定的影响。
Objective To explore the correlation between subjective symptoms and clinical indicators in the patients with dry eyes.Methods A total of 239 dry eye patients(239 eyes)was scored by OSDI(eye surface disease index).Meanwhile,the related signs of dry eye such as fluorescein staining of the cornea(FL),break-up time(BUT)and Schirmer I test(SIT)were evaluated.Results There was no significant correlation between ODSI score and FL,BUT,SIT and age in 239 patients with dry eyes(r=0.044,0.011,0.011 and 0.048,P>0.05).The age was negatively correlated to BUT and SIT(r=-0.154 and-0.251,P<0.05)and positively correlated with FL(r=0.140,P<0.05).The dry eye was negatively correlated with SIT(r=-0.203,P<0.05),visual fluctuation was positively correlated with FL(r=0.163,P<0.05),increased secretion was positively correlated with FL(r=0.139,P<0.05).The other dry eye symptoms were not significantly correlated with FL,BUT and SIT(P>0.05).Conclusion Most of the patients with dry eye have a poor correlation between subjective symptoms and objective examination,which may have a certain impact on the diagnosis and treatment of dry eye.
作者
罗丹
高卫萍
LUO Dan;GAO Weiping(Department of Ophthalmology,Affiliated Hospital,Nanjing University of Traditional Chinese Medicine,Nanjing 210029,CHINA)
出处
《江苏医药》
CAS
2020年第4期409-411,420,共4页
Jiangsu Medical Journal
基金
江苏省中医药局科研专项课题(ZX2016C1)。
