摘要
胶质瘤是脑内常见的侵袭性原发肿瘤,治疗效果不理想,寻找有效的治疗方法刻不容缓。已有研究证实,有些中药有抗脑胶质瘤作用,其中研究比较多的包括细辛醚、川芎嗪、当归、芍药苷、姜黄素、蛇床子素、类黄酮等,但这些药物的抗脑胶质瘤作用机制各异。全文综述脑胶质瘤的中药治疗现状,为胶质瘤的中药治疗提供参考。
Glioblastoma(GBM) is the common and aggressive primary brain tumor in adults with poor prognosis, and the more effective GBM therapeutic options are urgently needed. A large number of studies show that traditional Chinese medicine is effective in the treatment of GBM, and among of them many researches, both domestic and foreign, focus on the study of active constituents of traditional Chinese medicine, including B-asarone, 2,3,5,6-tetramathylpyrazine(TMP), angelica sinensis, paeoniflorin(PF), curcumin, Osthol and flavonoids, which have multiple mechanisms of anti-glioma effects. This paper reviews recent researches on current situation of traditional Chinese medicine in the treatment of GBM, and provides the reference for traditional Chinese medicine in the treatment of GBM.
作者
赵雯
徐宏治
ZHAO Wen;XU Hongzhi(Department of Anaesthesiology of Huashan Hospital affiliated to Fudan University,Shanghai 200040,China;Department of Neurosurgery of Huashan Hospital affiliated to Fudan University,Shanghai 200040,China)
出处
《上海医药》
CAS
2020年第10期3-7,共5页
Shanghai Medical & Pharmaceutical Journal
基金
上海市科学技术委员会医学重点项目(16411954100)
上海市科学技术委员会科研计划项目(16140903100)。
关键词
胶质瘤
中药
活性成分
机制
glioma
traditional Chinese medicine
active constituent
mechanism
