摘要
目的分析评价应用硫酸羟氯喹治疗风湿病的临床效果。方法回顾性分析本院2015年6月-2019年5月期间收治的206例风湿病患者的临床资料,所有患者均在甲氨蝶呤治疗基础上加用硫酸羟氯喹治疗,治疗后对患者的临床疗效及不良反应进行评价。结果患者治疗后关节压痛数及关节肿胀数较治疗前明显减少,差异有统计学意义(P<0.05),此外治疗后疼痛症状得到了显著缓解,疼痛评分较治疗前明显降低,差异有统计学意义(P <0.05),患者治疗总有效率为95.6%。结论硫酸羟氯喹治疗风湿病的临床疗效确切,且用药安全性较高,与甲氨蝶呤联合应用能够提高临床治疗效果。
Objective To analyze and evaluate the clinical effect of hydroxychloroquine sulfate in the treatment of rheumatism. Methods The clinical data of 206 patients with rheumatism admitted to our hospital from June 2015 to May 2019 were retrospectively analyzed. All patients were treated with hydroxychloroquine sulfate on the basis of methotrexate. The clinical efficacy and adverse reactions were evaluated after treatment. Results After treatment, the number of tenderness and swelling of joints were significantly reduced(P < 0.05), after treatment, the pain symptoms was significantly relieved,the pain score was significantly reduced(P < 0.05), and the total effective rate was 95.6%. Conclusion Hydroxychloroquine sulfate is effective and safe in the treatment of rheumatism. The combination of methotrexate and hydroxychloroquine sulfate can improve the clinical efficacy and can be widely used in clinic.
作者
马凤云
MA Fengyun(Department of Rheumatology and Immunology,Shijingshan Hospital,Beijing 100041,China)
出处
《中国继续医学教育》
2020年第14期163-164,共2页
China Continuing Medical Education
关键词
风湿病
甲氨蝶呤
硫酸羟氯喹
临床
疗效
不良反应
rheumatism
methotrexate
hydroxychloroquine sulfate
clinical
efficacy
adverse reactions
