摘要
目的探究优化后适应术式对急诊经皮冠状动脉介入术(PCI)急性心肌梗死患者心肌再灌注损伤的影响。方法选取2018年3月~2019年9月我院收治的进行急诊PCI的60例急性心肌梗死患者作为研究对象,将所有患者按照随机数字表法分为对照组(30例)和优化组(30例)。对照组患者实施常规的PCI治疗,优化组患者实施优化后适应术式的PCI治疗。比较两组患者院内最高和出院前的肌酸激酶同工酶(CK-MB)和氨基末端脑钠肽前体(NT-proBNP)水平的差值(△CK-MB、△NT-proBNP),比较两组患者术后及术后1个月心脏彩超进行相关指标。结果优化组患者△CK-MB、△NT-proBNP高于对照组,差异有统计学意义(P<0.05)。术后即刻,两组患者左心房内径(LA)、左心室舒张期内径(LVDD)、左心室收缩期内径(LVDS)、射血分数(EF)水平比较,差异无统计学意义(P>0.05)。术后1个月,优化组患者LVDS和EF值高于对照组,差异有统计学意义(P<0.05)。结论对急性心肌梗死患者实施优化后适应术式的PCI治疗,能够有效改善患者心肌状态,提高心功能水平,达到更好的治疗效果。
Objective To explore the influence of optimized operation mode on myocardial reperfusion injury in patients with acute myocardial infarction undergoing emergency percutaneous coronary intervention(PCI).Methods From March 2018 to September 2019,60 patients with acute myocardial infarction who underwent emergency PCI were selected as the study objects.All patients were divided into control group(30 cases)and optimization group(30 cases)according to random number table method.The patients in the control group were treated with conventional PCI,and the patients in the optimization group were treated with PCI which was suitable for comfort.The differences of creatine kinase isoenzyme(CK-MB)and amino terminal pro brain natriuretic peptide(NT-proBNP)between the two groups(△CK-MB,△NT-proBNP)were compared.The indexes of color Doppler echocardiography were compared between the two groups.Results The△CK-MB and△NT-proBNP in the optimized group were higher than those in the control group,the differences were statistically significant(P<0.05).Immediately after surgery,there were no significant differences between the two groups in left atrial diameter(LA),left ventricular diastolic diameter(LVDD),left ventricular systolic diameter(LVDS)and ejection fraction(EF)(P>0.05).One month after the operation,the LVDS and EF of the patients in the optimization group were higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion The optimized PCI for patients with acute myocardial infarction can effectively improve the myocardial status and improve the level of cardiac function,so as to achieve better therapeutic effect.
作者
林佑妮
杨敏
蔡裕福
蓝新平
LIN You-ni;YANG Min;CAI Yu-fu;LAN Xin-ping(The Fourth Department of Cardiovascular Internal Medicine,People′s Hospital of Meizhou City,Guangdong Province,Meizhou 514031,China)
出处
《中国当代医药》
2020年第12期70-73,共4页
China Modern Medicine
关键词
经皮冠状动脉介入术
优化后适应术式
心肌再灌注损伤
急诊
Percutaneous coronary intervention
Optimized post-adaptive procedure
Myocardial reperfusion injury
Emergency
