摘要
目的:探析尿微量白蛋白检测于阻塞性睡眠呼吸暂停低通气综合征(Obstructive Sleep Apnea Hypopnea Syndrome,OSAHS)患者早期肾损伤评估中的应用价值。方法:选取2018年5月至2019年6月福建医科大学附属第二医院收治的OSAHS患者84例作为研究对象,随机分为观察组和对照组,其中观察组44例,对照组40例,比较2组患者临床治疗与呼吸睡眠监测指标结果。结果:2组的舒张压(DBP)、收缩压(SBP)、身体质量指数(BMI)、身高、性别及年龄比较,差异无统计学意义(P>0.05);观察组尿微量白蛋白(UMA)、睡眠呼吸暂停指数(AHI)显著高于对照组,而最低脉氧饱和度(LSaO2)、平均脉氧饱和度(MSaO2)则明显低于对照组,2组比较差异有统计学意义(P<0.05)。结论:OSAHS患者的UMA水平可用于判断患者是否存在早期肾损伤。
Objective:To evaluate the value of urinary microalbumin in early renal injury assessment in patients with Obstructive Sleep Apnea Hypopnea Syndrome(OSAHS).Methods:A total of 84 OSAHS patients admitted to the second affiliated hospital of fujian medical university were selected as the study objects,and were randomly divided into the observation group and the control group,including 44 cases in the observation group and 40 cases in the control group.The clinical treatment and respiratory and sleep monitoring indexes of the two groups were compared.Results:Diastolic blood pressure(DBP),systolic blood pressure(SBP),body mass index(BMI),height,gender and age of the two groups showed no significant difference(P>0.05).The urinary microalbumin(UMA)and sleep apnea index(AHI)in group A were significantly higher than those in group B,while the lowest pulse oxygen saturation(LSaO2)and average pulse oxygen saturation(MSaO2)were significantly lower than those in group B(P<0.05).Conclusion:UMA level in OSAHS patients can be used to determine whether there is early renal injury.
作者
黄晓晖
HUANG Xiaohui(The second affiliated hospital of fujian medical university,Quanzhou 362300,China)
出处
《世界睡眠医学杂志》
2020年第3期530-531,共2页
World Journal of Sleep Medicine
