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系统性红斑狼疮患者血清IgG、IgA、IgM水平与疾病活动度的相关性分析 被引量:3

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摘要 目的:分析系统性红斑狼疮患者血清免疫球蛋白G(IgG)、IgA、IgM水平与疾病活动度的相关性。方法:选择100例系统性红斑狼疮患者作为研究对象,根据系统性红斑狼疮活动度评分(SLEDAI)将其分为轻度活动组(5≤SLEDAI≤9)33例、中度活动组(10≤SLEDAI≤14)46例和重度活动组(SLEDAI≥15)21例。比较三组血清IgG、IgA、IgM水平和SLEDAI评分,分析系统性红斑狼疮患者血清IgG、IgA、IgM水平与SLEDAI的相关性。结果:轻度活动组IgG、IgA水平及SLEDAI评分最低,其次是中度活动组,重度活动组最高,差异均有统计学意义(P<0.05);轻度活动组IgM水平最高,其次是中度活动组,重度活动组最低,差异均有统计学意义(P<0.05);系统性红斑狼疮患者血清IgG、IgA水平与SLEDAI评分呈正相关,IgM水平与SLEDAI评分呈负相关(P<0.05)。结论:系统性红斑狼疮患者IgG、IgA水平与疾病严重程度呈正相关,IgM水平与疾病严重程度呈负相关。
作者 周凤
机构地区 睢县中医院
出处 《中国民康医学》 2020年第7期6-7,共2页 Medical Journal of Chinese People’s Health
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