摘要
目的探讨Neuroform EZ支架治疗颅内动脉瘤的安全性和有效性。方法回顾性分析2016年7月至2018年7月解放军总医院第一医学中心采用Neuroform EZ支架辅助栓塞治疗的39例(41枚)颅内动脉瘤患者临床资料。根据术后即刻和复查DSA造影,评价Neuroform EZ支架在辅助动脉瘤栓塞中的安全有效性。结果 41枚动脉瘤中破裂13枚(31.7%),未破裂28枚(68.3%)。共应用Neuroform EZ支架47枚,均准确释放(100%)。其中单枚支架辅助栓塞35枚,双支架辅助栓塞6枚(双支架套叠4枚,Y形支架2枚)。栓塞后即刻mRaymond分级1级19枚(46.3%),2级7枚(17.0%),3a级11个枚(26.8%),3b级4枚(9.6%),其中破裂、未破裂动脉瘤分别为1级10枚(76.9%)、9枚(32.1%)。术中发生血栓事件1枚(2.4%)。术后6个月复查造影显示,mRaymond分级改善13枚,变差2枚,发现载瘤动脉再狭窄1枚(2.4%)。结论 Neuroform ZE支架辅助弹簧圈栓塞颅内动脉瘤安全有效,仍需多中心研究和远期随访验证。
Objective To investigate the safety and effectiveness of Neuroform EZ stent in the treatment of intracranial aneurysms. Methods The clinical data of 39 patients with intracranial aneurysms(41 aneurysms in total), who were admitted to the First Medical Center of Chinese PLA General Hospital of China to receive Neuroform EZ stent-assisted embolization during the period from July 2016 to July 2018, were retrospectively analyzed. Based on the immediate postoperative and follow-up reexamination DSA manifestations, the safety and effectiveness of Neuroform EZ stent in treating intracranial aneurysms were evaluated. Results Of the 41 aneurysms, 13(31.7%) were ruptured and 28(68.3%) were un-ruptured. A total of 47 Neuroform EZ stents were used, and all the 47 stents were accurately released(100%). Single stentassisted embolization was performed for 35 aneurysms, and dual stent-assisted embolization was carried out for 6 aneurysms, including 4 double stents and 2 Y-shaped stents. Immediate post-embolization mRaymond grading showed that grade I was achieved in 19 aneurysms(46.3%), grade Ⅱ in 7 aneurysms(17.0%), grade Ⅲa in 11 aneurysms(26.8%) and grade Ⅲb in 4 aneurysms(9.6%), among them grade I in ruptured group and in un-ruptured group was seen in 10 aneurysms(76.9%) and 9 aneurysms(32.1%) respectively. Intraoperative thrombus event occurred in treating one aneurysm(2.4%). Six months after treatment, angiography reexamination showed that improvement of mRaymond grade was obtained in 13 aneurysms and deterioration of mRaymond grade was seen in 2 aneurysms. Restenosis of the parent artery of aneurysm was detected in one aneurysm(2.4%). Conclusion For the treatment of intracranial aneurysms, Neuroform ZE stent-assisted coil embolization is safe and effective, although its long-term effect needs to validated with multi-center study and long-term follow-up.
作者
张荣举
王君
吕斌
杜志华
刘新峰
曹向宇
田成林
于生元
ZHANG Rongju;WANG Jun;Lü Bin;DU Zhihua;LIU Xinfeng;CAO Xiangyu;TIAN Chenglin;YU Shengyuan(Department of Neurology,First Medical Center of Chinese PLA General Hospital,Beijing 100853,China)
出处
《介入放射学杂志》
CSCD
北大核心
2020年第3期228-231,共4页
Journal of Interventional Radiology
基金
国家自然科学基金面上项目(81371296)。
