摘要
目的:探讨妊娠合并梅毒患者的治疗与围产儿预后之间的关系。方法:2018年6月-2019年6月收治妊娠合并梅毒患者54例,按疾病分期分为Ⅰ期组和Ⅱ期组,各27例。两组患者均给予苄星青霉素联合红霉素治疗。比较两组患者妊娠结局及新生儿梅毒感染率。结果:Ⅰ期组不良妊娠结局发生率及新生儿梅毒感染率均显著低于Ⅱ期组,差异有统计学意义(P<0.05)。结论:对妊娠合并梅毒患者不同临床分期实施抗病毒治疗,Ⅰ期患者不良妊娠结局及新生儿梅毒感染率显著低于Ⅱ期患者。因此,将梅毒筛查纳入到妊娠早期和孕前期常规检查中非常重要。
Objective:To explore the relationship between the treatment of pregnant patients with syphilis and prognosis of perinatal fetal.Methods:From June 2018 to June 2019,54 cases of pregnancy complicated with syphilis were enrolled,they were divided into stage I group and stage II group according to the stage of disease,with 27 cases in each group.Both groups were treated with benzathine penicillin combined with erythromycin.The pregnancy outcomes and neonatal syphilis infection rates between the two groups were compared.Results:The incidence of adverse pregnancy outcomes and neonatal syphilis infection rate in stage I group were significantly lower than in stage II group,the differences were statistically significant(P<0.05).Conclusion:Antiviral treatment is performed in different clinical stages of patients with pregnancy and syphilis.The adverse pregnancy outcomes and neonatal syphilis infection rates in patients with stageⅠare significantly lower than with stageⅡ.Therefore,it is important to include syphilis screening in the routine examination during early pregnancy and pre-pregnancy.
作者
王玲玲
Wang Lingling(Department of Gynaecology and Obstetrics,the Maternal and Child Health and Family Planning Service Centre of Tonghua City,Jilin Tonghua 134001)
出处
《中国社区医师》
2020年第13期87-88,共2页
Chinese Community Doctors
关键词
妊娠
梅毒
治疗
围产儿
预后
Pregnancy
Syphilis
Treatment
Perinatal fetal
Prognosis