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珍惜稀缺的高档抗菌药物,避免抗生素后时代全面来临 被引量:8

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摘要 在国内新型冠状病毒感染(COVID-19)疫情收官之际,让我们重新聚焦细菌耐药问题。随着耐碳青霉烯肠杆菌科细菌(CRE)、铜绿假单胞菌(C.RPA)和鲍曼不动杆菌(CRAB)等多重耐药革兰阴性杆菌(MDR-GNB)的流行,多重耐药菌感染的防控已成为全球范围内的重大公共卫生问题。在现有针对多重耐药菌的超广谱抗菌药物中,除碳青霉烯类已在我国应用20余年,替加环素(tigecycline)、多黏菌素(polymyxin)以及头抱他啶阿维巴坦(ceftazidine avibactam)则都是近几年上市或刚上市,或将是今后相当长时期内我们所能依赖用于救治MDR-GNB感染仅有的几个“战略武器”,可称得上是最宝贵且不可再生的“稀缺资源”。
出处 《中华急诊医学杂志》 CAS CSCD 北大核心 2020年第4期443-446,共4页 Chinese Journal of Emergency Medicine
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