摘要
重症肌无力(MG)是乙酰胆碱受体抗体介导的、细胞免疫依赖和补体参与的神经肌肉接头(NMJ)处传递障碍的自身免疫性疾病。MG与胸腺病变密切相关,故除内科治疗外,胸腺切除术是治疗MG的一种重要方式。本文通过查阅国内外最新文献,汇集京津冀十余位本领域专家经验,针对MG的抗体分型、术前检查、手术指征、手术方式、术后治疗及随访写成专家共识,希望能指导MG的外科治疗。
Myasthenia gravis(MG)is an autoimmune disease with dystransmission at the neuromuscular junction(NMJ),which is mediated by acetylcholine receptor antibody,dependent on cellular immunity and participated by complement.MG is closely related to thymic diseases,so in addition to the medical treatment,thymectomy is an important way to treat MG.Based on the latest literature at home and abroad,and the experience of more than ten experts in Beijing,Tianjin and Hebei,this paper has written an expert consensus on antibody typing,preoperative examination,surgical indications,surgical methods,postoperative treatment and follow-up of MG,hoping to guide the surgical treatment of MG.
出处
《天津医药》
CAS
北大核心
2020年第4期327-332,共6页
Tianjin Medical Journal
基金
天津市科技计划项目科技重大专项与工程(16ZXMJSY00030)
天津市自然科学基金京津冀专项项目(19JCZDJC64400(Z))。
关键词
重症肌无力
胸腺
外科治疗
myasthenia gravis
thymus
surgical treatment
