摘要
微电极作为外部电子设备与内部神经核团之间的接口,在动物机器人、深度脑刺激、神经假体等方面都起着重要的作用。针对现有微电极制作装置价格高昂且制作工艺复杂等问题,本文提出了一种基于开源电子原型平台(Arduino)和三维打印技术的双绞微电极制作装置,并验证了其电极制作性能及神经刺激性能。实验结果表明,在微电极制作过程中,电极丝的正向绞合圈数一般应设置为其长度的1.8倍左右较适宜,逆向绞合圈数与长度无关,一般为5左右。与同类产品相比,本文所提装置不仅价格低廉、制作简单并具有较好的扩展性,对于微电极制作的个性化、普及化以及降低实验成本都有着积极的促进意义。
As an interface between external electronic devices and internal neural nuclei, microelectrodes play an important role in many fields, such as animal robots, deep brain stimulation and neural prostheses. Aiming at the problem of high price and complicated fabrication process of microelectrode, a microelectrode twisting machine based on open source electronic prototyping platform(Arduino) and three-dimensional printing technology was proposed, and its microelectrode fabrication performance and neural stimulation performance were verified. The results show that during the fabrication of microelectrodes, the number of positive twisting turns of the electrode wire should generally be set to about 1.8 times of its length, and the number of reverse twisting rings is independent of the length, generally about 5.Moreover, compared with the traditional instrument, the device is not only inexpensive and simple to manufacture, but also has good expandability. It has a positive significance for both the personalization and popularization of microelectrode fabrication and the reduction of experimental cost.
作者
刘新玉
王东云
赵恩辉
马梅方
师丽
LIU Xinyu;WANG Dongyun;ZHAO Enhui;MA Meifang;SHI Li(School of Intelligent Manufacturing,Huanghuai University,Zhumadian,Henan 463000,P.R.China;School of Information Science and Technology,Department of Automation,Tsinghua University,Beijing 100084,P.R.China;Jiangsu Yige Bio-tech Ltd,Nanjing 210000,P.R.China;Henan Key Laboratory of Brain Science and Brain-Computer Interface Technology,Zhengzhou University,Zhengzhou 450001,P.R.China)
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2020年第2期317-323,共7页
Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(61673353)
河南省科技厅科技攻关项目(182102210099)
黄淮学院国家级科研项目培育基金(XKPY-2018006)。
关键词
双绞微电极
三维打印
神经刺激
动物机器人
twisted microelectrode
three dimensional printing
neural stimulation
animal robot
