摘要
目的:分析影响急性自发性荨麻疹(ASU)转归为慢性自发性荨麻疹(CSU)的危险因素。方法:回顾性分析本院2018年11月至2019年10月178例ASU患者的人口学信息、发病季节、初发病程、自诉可疑过敏原、自体血清皮肤试验(ASST)、7日荨麻疹活动度评分(UAS7)、血常规、血清总IgE测定、治疗药物,Logistic回归分析ASU转归为CSU的危险因素。结果:178例ASU中42例(23.60%)转归为CSU,单因素分析自诉食物过敏(P<0.001)、 ASST试验阳性(P<0.001)、初发病程(P<0.001)与ASU患者转归为CSU具有相关性;多因素Logistics回归分析示自诉食物过敏(P=0.029)、ASST试验阳性(P=0.043)、初发病程长(P<0.001)均是影响ASU转归为CSU的独立危险因素。结论:食物过敏、ASST试验阳性、初发病程长是ASU患者转归为CSU的危险因素。
Objective:To analyze the risk factors of acute spontaneous urticaria(ASU) developing into chronic spontaneous urticaria(CSU) in 178 patients. Methods:The data of 178 patients with ASU in Weifang People’s Hospital from November 2018 to October 2019 was analyzed, including age, sex, first onset season and duration, self-report of suspected allergens, autologous serum skin test(ASST), urticaria activity score 7(UAS7), blood routine test, serum total IgE level and therapeutic drugs. Results:Of 178 patients with ASU, 42(23.60%) developed into CSU. The univariate analysis showed food allergy(P<0.001), positivity for ASST(P<0.001) and long first onset duration(P<0.001) were associated with ASU developing into CSU. Logistic regression analysis showed that food allergy(P=0.029), positivity ASST result(P<0.043) and long first onset duration(P<0.001) were risk factors for ASU developing into CSU. Conclusion:Food allergy, positivity for ASST and long first onset duration are the risk factors for ASU developing into CSU.
作者
孙艳茹
刘文博
范梦娇
张凤杰
王振华
SUN Yanru;LIU Wenbo;FAN Mengjiao;ZHANG Fengjie;WANG Zhenhua(Clinical College of Weifang Medical University,Weifang 261053,China;Department of Dermatology,Weifang People s Hospital,Weifang 261041,China)
出处
《中国麻风皮肤病杂志》
2020年第4期210-213,共4页
China Journal of Leprosy and Skin Diseases
