摘要
坏疽性脓皮病是一种少见的、非感染性的嗜中性皮肤病,是以皮肤破坏性溃疡为特征的反应性炎症性皮肤病,目前病因尚不明确,多种炎症因子刺激、中性粒细胞功能异常及遗传易感性等可能与此相关。皮损起初为炎性丘疹、水疱、脓疱或结节,后迅速破裂形成大的糜烂或溃疡,常伴有剧烈疼痛。坏疽性脓皮病可单独发病,也可伴系统损害性疾病,包括血液系统疾病、炎症性肠病、类风湿性关节炎及实体恶性肿瘤等,现对1例骨髓增生异常综合征合并坏疽性脓皮病的患者资料进行回顾报告,以增加对坏疽性脓皮病的认识。
Pyoderma gangrenosum is a rare and non-infectious neutrophilic dermatosis,or inflammatory or allergic dermatosis,featuring destructive skin ulcers.Its pathogenesis remains unclear,and skin stimulation from multiple inflammatory factors,abnormal neutrophil function and a genetic predisposition may associate with this malady.Inflammatory papules,blisters,pustules and nodules initially appear in skin lesions,which are immediately broken and form a major erosion or skin ulcer accompanied by severe pain.Pyoderma gangrenosum can occur independently or with diseases of other systems encompassing hematological diseases,inflammatory bowel disease,rheumatoid arthritis and malignant solid tumors.In this study,we retrospectively reported a case of myelodysplastic syndrome complicated with pyoderma gangrenosum with detailed clinical information for better understanding the disease.
作者
黄金娥
陈然
HUANG Jin'e;CHEN Ran(Grade 2017 master at Graduate School,Hunan University of Chinese Medicine,Changsha410007,China;Department of Cardiovascular Medicine,Changsha Central Hospital Affiliated to University of South China,Changsha410007,China)
出处
《中国现代医生》
2020年第6期162-164,共3页
China Modern Doctor
