摘要
目的分析妇科肿瘤患者围术期内下肢深静脉血栓(DVT)形成危险因素,以期为妇科肿瘤患者DVT防治提供科学参考。方法回顾性分析2016年2月至2019年2月在本院接受妇科肿瘤手术治疗且临床资料完整的295例患者术前、术中及术后相关临床资料及临床指标。使用单因素和多因素回归分析法筛选影响患者术前和术后DVT发生的危险因素。结果术前15例患者形成DVT,占比5.08%;术后23例形成DVT,占比7.80%。单因素分析和Logistic回归分析显示,年龄、BMI、合并高血压、合并糖尿病、肿瘤性质、血小板数目、D二聚体含量是术前DVT发生的危险因素,术前补液是DVT发生的保护性因素(P<0.05)。单因素分析和Logistic回归分析显示,术前DVT发生、麻醉方式、术中体位、手术时间、术后止血药物使用、术后卧床时间是术后DVT发生的危险因素(P<0.05)。结论妇科肿瘤患者术前、术后均有较高DVT发生风险。需加强对年龄≥60岁、超重、合并高血压、合并糖尿病、肿瘤恶性、血小板数目≥300×10^9/L、D二聚体含量≥300 ng/mL、全麻、仰卧位、手术时间≥4 h、术后使用止血药和卧床时间≥5 d的妇科肿瘤患者管理,预防DVT发生。
Objective To analyze the risk factors of deep venous thrombosis(DVT)in patients with gynecologic tumors during perioperative period,in order to provide scientific reference for the prevention and treatment of DVT in gynecologic tumor patients.Methods The clinical data and clinical indicators of preoperation,intraoperation and postoperation of 295 patients who underwent gynecologic oncology surgery and had complete clinical data in our hospital from 2016 February to February 2019 were analyzed retrospectively.Univariate and multivariate regression analysis were used to screen for risk factors affecting preoperative and postoperative DVT formation in patients.Results DVT was formed in 15 cases(5.08%)before operation and in 23 cases(7.80%)after operation.The univariate analysis and Logistic regression analysis showed that age,BMI,hypertension,diabetes,tumor character,platelet number,D-dimer content were the risk factors of DVT formation before operation,while preoperative fluid infusion was the protective factor of DVT formation(P<0.05).The univariate analysis and Logistic regression analysis showed that the occurrence of DVT before operation,anesthesia mode,posture during operation,operation time,use of hemostatic drugs and bed time after operation were the risk factors of DVT formation after operation(P<0.05).Conclusion Gynecologic tumor patients are at risk from higher DVT formation before and after after operation.It is necessary to strengthen the management of gynecological tumor patients with age≥60 years old,overweight,with hypertension,diabetes,tumor malignancy,platelet number≥300×10^9/L,D-dimer content≥300 ng/mL,general anesthesia,supine position,operation time≥4 h,use hemostatic drugs and bed time after operation≥5 d so as to prevent DVT formation.
作者
任婉婷
郭维娟
REN Wan-ting;GUO Wei-juan(Obstetrics and Gynecology Department,Xi'an Beihuan Hospital,Xi'an 710032;Obstetrics and Gynecology Department,Xi'an Fifth Hospital,Xi'an 710082,China)
出处
《临床医学研究与实践》
2020年第7期24-26,共3页
Clinical Research and Practice
关键词
妇科肿瘤
深静脉血栓
危险因素
gynecologic tumors
deep vein thrombosis
risk factors
