摘要
目的比较微波消融术和传统手术治疗良性甲状腺结节的效果和安全性。方法将我院2017年7月至2019年8月收治的119例良性甲状腺结节患者随机分为试验组(n=60,微波消融术治疗)和对照组(n=59,传统手术治疗)。比较两组的治疗效果与安全性。结果试验组术中出血量显著少于对照组,手术时间及术后住院时间显著短于对照组(P<0.05)。试验组术后TSH、血清FT3、FT4、TT4水平优于对照组(P<0.05)。术后,两组IL-6、TNF-α、CRP水平均升高,但试验组显著低于对照组(P<0.05)。试验组的并发症总发生率低于对照组(P<0.05)。结论微波消融术治疗良性甲状腺结节的效果较好,能有效缩短手术时间,减少术中出血,促使患者更快康复出院,且对患者甲状腺激素水平影响较小,术后炎症反应较轻,并发症较少,值得临床应用推广。
Objective To compare the efficacy and safety of microwave ablation and traditional operation in the treatment of benign thyroid nodules.Methods A total of 119 patients with benign thyroid nodules admitted in our hospital from July 2017 to August 2019 were randomly divided into experimental group(n=60,microwave ablation)and control group(n=59,traditional operation).The therapeutic effects and safety of the two groups were compared.Results The intraoperative blood loss in the experimental group was significantly less than that in the control group,and the operation time and postoperative hospital stay were significantly shorter than those in the control group(P<0.05).The levels of TSH,serum FT3,FT4 and TT4 in the experimental group were significantly better than those in the control group(P<0.05).After operation,the levels of IL-6,TNF-αand CRP in the two groups all increased,but those of the experimental group were significantly lower than the control group(P<0.05).The total incidence of complications in the experimental group was lower than that in the control group(P<0.05).Conclusion Microwave ablation is effective in the treatment of benign thyroid nodules,it can effectively shorten the operation time,reduce intraoperative bleeding,promote patients to recover and discharge faster,and has less impact on patients'thyroid hormone level,with less postoperative inflammatory response and complications,which is worthy of clinical application and promotion.
作者
徐佳华
XU Jia-hua(the People's Hospital of Shanwei,Shanwei 516600,China)
出处
《临床医学研究与实践》
2020年第11期66-68,共3页
Clinical Research and Practice
关键词
良性甲状腺结节
微波消融术
传统手术
甲状腺激素
炎性因子
benign thyroid nodule
microwave ablation
traditional operation
thyroid hormone
inflammatory factor
