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从伏气温病理论探讨乙型病毒性肝炎慢性化机制 被引量:12

Mechanism of Chronic Hepatitis B Virus from Theory of Warm Disease Due to Latent Qi
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摘要 正气不足、邪气内伏是伏气温病的主要病机。乙型病毒性肝炎慢性化、难以根治的主要原因是由于乙肝病毒的ccc DNA潜伏肝细胞核内和机体免疫应答不全,这与伏气温病相类似。再者邪伏之所-膜原与"脏真散于肝,肝藏筋膜之气"密切相关,因膜原具有分布的广泛性、系统的复杂性,与脏腑之间的联系具有紧密性及中介性,这使得慢性肝病的治疗变得颇为棘手。中医学认为慢性乙型肝炎由湿热疫毒之邪内侵,当人体正气不足无力抗邪时发病,常因外感、情志、饮食、劳倦而诱发。正气不足、邪气内伏是乙型病毒性肝炎慢性化机制。 Insufficient vital Qi and latent evils are the main pathogenesis of warm disease.The main reason for the chronic hepatitis B is the incompatibility of the cccDNA of the hepatitis B virus in the nucleus and the immune response of the body,which is similar to warm disease caused by latent Qi.Furthermore,the place where the evil is latent in-the membrane is closely related to the“the essence scattered in the liver and the tendon Qi stored in the liver”.Because the membrane has a wide distribution and system complexity,and the connection with Zang-fu organs is tight,making the treatment of chronic liver disease quite difficult.Traditional Chinese medicine thinks that chronic hepatitis B is caused by damp-heat attacking internally.When the human body is lacking in strength and resistance to obnoxious,it is often caused by exogenous feelings,emotions,dietand fatigue.Insufficient vital Qi and latent evils are habitual mechanisms of hepatitis B virus.
作者 周峰峰 陈逸云 商斌仪 高月求 卓蕴慧 ZHOU Fengfeng;CHEN Yiyun;SHANG Binyi;GAO Yueqiu;ZHUO Yunhui(Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
出处 《辽宁中医杂志》 CAS 2020年第2期88-89,共2页 Liaoning Journal of Traditional Chinese Medicine
基金 “十三五”科技重大专项课题(2018ZX10725506) 中药综合干预轻微肝性脑病前瞻性队列研究(20134103)。
关键词 慢性乙型病毒性肝炎 伏气温病 膜原 chronic hepatitis B warm disease due to latent Qi membrane
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