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枯草杆菌二联活菌颗粒联合蒙脱石散早期预防新生儿黄疸的疗效及安全性分析

Analysis of Efficacy and Safety of Bacillus Subtilis Bifidobacterium Granules Combined with Montmorillonite Powder in Early Prevention of Neonatal Jaundice
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摘要 目的研究蒙脱石散联合枯草杆菌二联活菌颗粒对新生儿黄疸的临床效果.方法选取2017年9月至2018年9月山东省曲阜市妇幼保健院收治的100例黄疸新生儿作为研究对象,将其分为实验组和对照组,各50例.实验组患者采用蒙脱石散联合枯草杆菌二联活菌颗粒治疗,对照组仅采用枯草杆菌二联活菌颗粒治疗,比较两组新生儿治疗一周后的黄疸情况.结果实验组的治疗效果优于对照组(P<0.05),治疗1周后,实验组不良反应率明显低于对照组(P<0.05),实验组新生儿的黄疸消退时间短于对照组,新生儿临床症状改善用时显著低于对照组(P<0.05).结论蒙脱石散结合枯草杆菌二联活菌颗粒对新生儿黄疸能够有效缩短治疗时间,治疗效果显著,由此可见两种药物联合使用能够有效预防新生儿黄疸. Objective To study the clinical effect of montmorillonite powder combined with Bacillus subtilis bifidobacterium granules on neonatal jaundice.Methods From September 2017 to September 2018,100 neonates with jaundice admitted to Qufu Maternal and Child Health and Family Planning Service Center were selected as the research objects,and divided into experimental group and control group,50 cases each.The experimental group was treated with montmorillonite powder combined with Bacillus subtilis bifidobacterium granules,while the control group was treated with Bacillus subtilis bifidobacterium granules only.The jaundice situation of the two groups after one week of treatment was compared.Results The therapeutic effect of the experimental group was better than that of the control group(P<0.05).After one week of treatment,the adverse reaction rate of the experimental group was significantly lower than that of the control group(P<0.05).The jaundice subsidence time of the experimental group was shorter than that of the control group,and the improvement time of the clinical symptoms of the newborn was significantly lower than that of the control group(P<0.05).Conclusion Montmorillonite powder combined with Bacillus subtilis bifidobacterium granules can effectively shorten the treatment time of neonatal jaundice,and the therapeutic effect is remarkable.The combined use of the two drugs can effectively prevent neonatal jaundice and is worth popularizing.
作者 丛惠芹 CONG Huiqin(Qufu Maternal and Child Health and Family Planning Service Center,Jining,Shandong 273100,China)
出处 《大医生》 2019年第20期135-136,共2页 Doctor
关键词 新生儿黄疸 蒙脱石散 枯草杆菌二联活菌颗粒 安全性 neonatal jaundice montmorillonite powder mommy love safety

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