摘要
目的探讨外周血血小板和异型淋巴细胞测定对早期肾综合征出血热的诊断价值。方法选取2015年1月1日-2018年12月1日在衢州市人民医院确诊为肾综合征出血热的46例患者,经Sysmex2100血常规分析仪进行血常规检测,并将外周血涂片进行染色镜检,计算出异型淋巴细胞所占比例。结果46例肾综合征出血热患者疾病早期临床症状和体征复杂多样,通过疾病早期血小板减少及异型淋巴细胞增多2项指标的联合检测,血小板减少而异型淋巴细胞不增多的占10.9%,血小板不减少而异型淋巴细胞增多的占13.0%,血小板减少而异型淋巴细胞增多的占76.1%。结论血小板联合外周血异型淋巴细胞测定可明显提高肾综合征出血热诊断的及时性和准确性,对早期非典型的肾综合征出血热患者更具有临床参考价值。
Objective To explore the diagnostic value of platelet combined with peripheral blood lymphocyte test in early hemorrhagic fever with renal syndrome.Methods Forty-six patients with hemorrhagic fever and renal syndrome diagnosed in Quzhou People's Hospital from January 1,2015 to December 1,2018 were examined by Sysmex2100 blood routine analyzer,and peripheral blood smears were examined by staining microscopy to calculate the proportion of heterotypic lymphocytes.Results The early clinical symptoms and signs of 46 patients with hemorrhagic fever and renal syndrome were complex and varied.The combined detection of thrombocytopenia and atypical lymphocyte proliferation in the early stage of the disease showed that 10.9%of the patients had thrombocytopenia but no increase of atypical lymphocyte,13.0%had no decrease of platelet but increase of atypical lymphocyte,and 76.1%had thrombocytopenia and increase of atypical lymphocyte.Conclusion Platelet combined with peripheral blood atypical lymphocyte assay can significantly improve the diagnostic timeliness and accuracy of hemorrhagic fever with renal syndrome.It has more clinical reference value for patients with atypical and mild hemorrhagic fever and renal syndrome.
作者
郑小金
潘清波
王慧芬
张敏波
陈秀花
ZHENG Xiao-jin;PAN Qing-bo;WANG Hui-fen;ZHANG Min-bo;CHEN Xiu-hua(Clinical Laboratory,Quzhou People's Hospital,Quzhou,Zhejiang 324000,China)
出处
《中国卫生检验杂志》
CAS
2020年第6期707-709,共3页
Chinese Journal of Health Laboratory Technology
关键词
肾综合征出血热
流行性出血热
异型淋巴细胞
血小板
Hemorrhagic fever with renal syndrome
Epidemic hemorrhagic fever
Atypical lymphocyte
Platelet
