摘要
我国大于60岁老年人高尿酸血症的患病率大约为5.5%~19.3%。随着我国人口老龄化的进展,高尿酸血症的发病人口会不断上升。针对无症状性高尿酸血症的老年人是否需要积极降尿酸治疗,目前临床上尚无指南依据。本文从尿酸的代谢过程及病理、生理、老年人高尿酸血症合并共病的治疗策略、具体的治疗流程及药物治疗进展等方面进行综述。
The prevalence of hyperuricemia in elderly population aged over 60 years in China ranges from 5.5%-19.3%.With the population ageing,the number of the patients with hyperuricemia can be expected to grow.Whether elderly patients with asymptomatic hyperuricemia need active uric acid-lowering therapy is still a debatable entity because of lacking relevant clinical guidelines.In this paper,the metabolic process of uric acid,pathophysiologic mechanism of hyperuricemia,the treatment principle of hyperuricemia in combination with different comorbidities,and specific therapeutic schedules for asymptomatic hyperuricemia as well as drug therapy progress were reviewed as follows.
作者
张瑞华
秦明照
Zhang Ruihua;Qin Mingzhao(Department of Geriatrics,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2020年第2期233-237,共5页
Chinese Journal of Geriatrics
关键词
无症状高尿酸血症
治疗
Asymptomatic hyperuricemia
Therapy
