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趋化因子CXC亚族与疾病发生发展研究的新进展 被引量:2

Recent advances in the association between chemokine CXC subgroup and disease development
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摘要 趋化因子是一种能够诱导白细胞移行到病变部位的小分子蛋白质。趋化因子分为四类亚族,CXC亚族就是其中一种。CXC亚族与肿瘤性疾病、糖尿病及糖尿病相关疾病和肝炎等疾病的进展有密切关联,通过检测不同疾病患者的不同CXC亚族成员的表达水平,了解疾病相关的机制,为疾病的治疗提供新的治疗靶点。同时也能够监测治疗效果,可能作为判断疾病预后的新的标志物。 Chemokine is a small molecule protein that can induce leukocytes to migrate to the lesion site.Chemokines are divided into four subgroups,one of which is the CXC subgroup.CXC subgroup is closely related to the progression of cancer,diabetes,diabetes-related diseases and hepatitis.By detecting the expression levels of different CXC subgroup members in different diseases,we can understand the disease-related mechanisms and provide new therapeutic targets for the treatment of diseases.At the same time,it can also monitor the therapeutic effect,and may be used as a new marker for judging the prognosis of the disease.
作者 富宏然 莫迪 金红 李梦雨 夏燕杰 FU Hong-ran;MO Di;JIN Hong;LI Meng-yu;XIA Yan-jie(Clinic Lab,Hongqi Hospital Affiliated to Mudanjiang Medical University,Mudanjiang 157011,China;First School of Clinical Laboratory,Mudanjiang Medical University,Mudanjiang 157011,China)
出处 《实验室科学》 2020年第1期1-3,共3页 Laboratory Science
关键词 趋化因子 肿瘤 分子标志物 chemokine tumor molecular marker
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