摘要
根皮苷是民间中药多穗石柯的主要活性成分之一。大量研究表明,根皮苷具有抗氧化、降血糖、抗炎、抗肿瘤、抗脑缺血等多种药理作用。该文结合国内外研究报道,综述近年来根皮苷药理作用及其可能的作用机制研究进展,以期为进一步研究根皮苷提供参考。
Phlorizin is a major active component of Lithocarpus polystachyus Rehd,which is a kind of Chinese folkloric medicine. Accumulating evidence demonstrate that phlorizin exhibits multiple pharmacological effects including anti-oxidative effect,hypoglycemic effect, anti-inflammation, anti-tumor effect and anti-ischemia stroke.Based on domestic and foreign research reports,the pharmacological effects and its underlying molecular mechanisms of phlorizin were reviewed in this article.It will provide clue and evidence for research and development of phlorizin.
作者
马琮鉴
高健美
孔浩
徐应淑
MA Congjian;GAO Jianmei;KONG Hao;XU Yingshu(School of Pharmacy,Zunyi Medical University,Zunyi 563000,China;Qilu Medical University,Zibo 255213,China)
出处
《医药导报》
CAS
北大核心
2020年第3期360-364,共5页
Herald of Medicine
基金
教育部创新团队资助项目(IRT_17R113)
大学生创新创业计划项目(ZKDC2018007)
山东省高等学校科技计划项目(J13LL61)。
关键词
根皮苷
抗氧化
降血糖
抗炎
抗肿瘤
抗缺血性脑卒中
Phlorizin
Anti-oxidative effect
Hypoglycemic effect
Anti-inflammation
Anti-tumor effect
Anti-ischemia stroke
