摘要
目的探讨胸腔镜手术治疗对肺癌患者术后应激反应的影响。方法选取2018年2月~2019年4月间我院收治的150例肺癌患者,随机分为观察组与对照组,每组75例,对照组患者采用传统开胸手术,观察组患者采用胸腔镜手术治疗,比较两种治疗方式对患者应激反应的影响。结果观察组患者治疗总有效率89.33%(67/75),对照组患者治疗总有效率72.00%(54/75),组间比较差异有统计学意义(P<0.05)。术前,两组在皮质醇、生长激素、ACTH、PGE2及P物质水平等应激反应指标上比较差异均无统计学意义(P>0.05);术后1 d、术后7 d两组皮质醇、PGE2及P物质水平应激指标上比较差异均有统计学意义(P<0.05)。结论与传统开胸手术相比,胸腔镜肺叶切除手术在肺癌患者的治疗过程中能够降低患者的应激反应,值得临床推广应用。
Objective To investigate the efficacy of thoracoscopic surgery for lung cancer and its effect on postoperative stress response. Methods 150 patients with lung cancer admitted to our hospital from February 2018 to April 2019 were randomly divided into observation group and control group,with 75 patients in each group. The control group was treated with traditional thoracotomy. The observation group was treated with thoracoscopy surgery. The effects of two treatments on stress response in patients were compared. Results The total effective rate was 89.33%(67/75) in the observation group and 72.00%(54/75) in the control group,and the difference was statistically significant between the two groups(P<0.05). There were no differences of cortisol, growth hormone, ACTH, PGE2 and substance P between the two groups before the operation(P>0.05).1 d,7 d after the operation, there were significantly differences of cortisol, PGE2 and substance P between the two groups(P<0.05) Conclusion Compared with traditional thoracotomy, thoracoscopic lobectomy can reduce the stress response of patients with lung cancer during the treatment of lung cancer,which is worthy of clinical application.
作者
冯勇
FENG Yong(Department of Thoracic Surgery,Shenyang Tenth People's Hospital,Shenyang110044,China)
出处
《中国现代医生》
2020年第3期47-49,53,共4页
China Modern Doctor
