摘要
目的分析醋酸曲安奈德联合甲钴胺片治疗腰椎间盘突出症的临床价值。方法收集2016年5月—2017年10月诊治的84例腰椎间突出症患者的临床资料进行回顾性分析。按照不同的治疗方案将患者分为对照组和观察组,每组42例。对照组采用甲钴胺片治疗,观察组在对照组的基础上联合醋酸曲安奈德治疗。比较2组治疗后的临床疗效、疼痛视觉模拟评分法(VAS)评分、日本骨科协会下腰痛功能评价表(JOA)评分,并观察2组的腰痛复发和不良反应发生情况。结果观察组临床总有效率明显高于对照组(P<0.05)。治疗后,2组的VAS评分较治疗前明显降低,且观察组明显低于对照组(P<0.05);治疗后,2组JOA评分较治疗前明显升高,且观察组明显高于对照组(P<0.05)。随访3个月和8个月时,观察组的复发率均明显低于对照组,且随访8个月时2组的复发率均明显高于随访3个月时(P<0.05)。2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论醋酸曲安奈德联合甲钴胺片治疗腰椎间盘突出症临床效果显著,可有效改善患者临床症状,且安全性高。
Objective To analyze the clinical value of Triamcinolone acetate combined with Mecobalamin tablets in the treatment of lumbar disc herniation(LDH).Methods The clinical data of 84 patients with LDH diagnosed between May 2016 and October 2017 were collected for retrospective analysis.According to different treatment plans,the patients were divided into control group and observation group,with 42 cases in each group.The control group was treated with Mecobalamin tablets,and the observation group was treated with Triamcinolone Acetate on the basis of the control group.The clinical effect,visual analogue scale(VAS)and Japanese Orthopaedic Association(JOA)score of the two groups were compared after treatment,and the recurrence and adverse reactions of low back pain in the two groups were observed.Results The total effective rate in the observation group was significantly higher than that in the control group(P<0.05).After treatment,VAS scores in the two groups were significantly lower than those before treatment,and the scores in the observation group were significantly lower than those in the control group(P<0.05).After treatment,JOA scores in the two groups were significantly higher than those before treatment,and the scores in the observation group were significantly higher than those in the control group(P<0.05).At 3 months and 8 months of follow-up,the recurrence rate in the observation group was significantly lower than that in the control group,and at 8 months of follow-up,the recurrence rate in both groups was significantly higher than that at 3 months of follow-up(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Triamcinolone Acetonide combined with Mecobalamin tablets has a significant clinical effect in the treatment of LDH,which can effectively improve the clinical symptoms of patients and has high safety.
作者
石明东
崔显峰
陈宇
SHI Ming-dong;CUI Xian-feng;CHEN Yu(The First Department of Osteology,Liaoyang Central Hospital,Liaoyang,Liaoning 111000,China)
出处
《解放军医药杂志》
CAS
2020年第3期96-99,共4页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
辽宁省自然科学基金(2015020369)。
关键词
醋酸曲安奈德
甲钴胺
腰椎间盘突出症
腰痛
复发
不良反应
Triamcinolone acetonide
Mecobalamin
Lumbar disc herniation
Low back pain
Recurrence
Adverse reactions
