摘要
随着膳食结构和生活方式的改变,肥胖的发病率显著升高。近年来,越来越多的研究表明,肠道菌群在肥胖及其代谢性疾病的发生过程中发挥重要作用。本文将阐述肠道菌群改变与肥胖发生的关系,肠道菌群紊乱引起肥胖的作用机制,并总结中医药通过影响肠道菌群干预肥胖的研究进展。
With the changes in dietary structure and lifestyle, the incidence of obesity has increased significantly. In recent years, increasing evidence shows that gut microbiota plays an important role in the development of obesity and related metabolic disorders. This article summarizes the relationship between gut microbiota and obesity, the underlying mechanisms for gut microbiota changes on obesity and related metabolic disorders. Furthermore, we review the progress of Chinese medicine in treating obesity by regulating gut microbiota.
作者
谢绍锋
黄莉吉
狄红杰
刘超
Xie Shaofeng;Huang Liji;Di Hongjie;Liu Chao(Department of Endocrinology,Jiangsu Province Hospital on Integration of Chinese and Western Medicine,Affiliated to Nanjing University of Chinese Medicine,Nanjing,210028,China;Department of Endocrinology,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2019年第11期2474-2479,共6页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
江苏省中医药局科技项目(FY201706):基于肠道菌群调节探讨中药小陷胸汤改善超重、肥胖2型糖尿病代谢紊乱作用机制,负责人:谢绍锋
国家科技部国家科技支撑计划(2015BAI12B14):中国成人糖尿病的发病危险因素、动态监测及综合防治,负责人:刘超。
关键词
中药治疗
肠道菌群
肥胖
2型糖尿病
traditional Chinese medicine
obesity
gut microbiota
type 2
diabetes
