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阿司匹林在高血压合并冠心病患者中的治疗价值 被引量:10

Therapeutic effects of aspirin on hypertension complicated by coronary heart disease
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摘要 目的分析阿司匹林在高血压合并冠心病患者中的治疗价值。方法选取2016年6月至2017年6月治疗的90例高血压合并冠心病患者,随机分为对照组和观察组,每组45例。对照组使用替米沙坦、硝酸异山梨酯片等常规药物治疗,观察组在对照组基础上加用阿司匹林。比较2组血压和血脂水平、心功能及左心室射血分数及疗效情况。结果治疗后,2组患者血压水平、血脂水平差异无统计学意义(P>0.05);观察组血液黏度显著低于对照组(P<0.05),左心室射血分数(LVEF)显著高于对照组(P<0.05);观察组疗效显著高于对照组(P<0.05)。结论阿司匹林有助于降低高血压合并冠心病患者的血液黏度,对提高患者心功能水平具有显著效果,应用价值较高。 Objective To investigate the therapeutic effects of aspirin on hypertension complicated by coronary heart disease.Methods A total of 90 patients with hypertension complicated by coronary heart disease who were treated in our hospital were randomly divided into control group(n=45)and observation group(n=45).The patients in control group were treated by conventional drugs including telmisartan and isosorbide dinitrate,however,the patients in observation group,on the basis of control group,were treated by oral aspirin.After treatment,the therapeutic effects were observed and compared between the two groups.Results After treatment,there were no significant differences in blood pressure and blood lipid levels between the two groups(P>0.05).The blood viscosity in observation group was significantly lower than that in control group(P<0.05),and the left ventricular ejection fraction(LVEF)was significantly higher than that in control group(P<0.05).Moreover the therapeutic effects in observation group were significantly better than those in control group(P<0.05).Conclusion Aspirin is helpful to reduce the blood viscosity of patients with hypertension complicated by coronary heart disease,which has significant effects in improving the level of cardiac function of patients,therefor,it is of great application value and is worthy of clinical promotion.
作者 庞庆春 PANG Qingchun(Guangwai Community Health Service Center,Xicheng District,Beijing 100143,China)
出处 《河北医药》 CAS 2020年第3期451-453,共3页 Hebei Medical Journal
关键词 阿司匹林 高血压 冠心病 aspirin hypertension coronary heart disease
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