摘要
目的分析双水平气道正压通气(BiPAP)无创呼吸机联合经管道雾化吸入布地奈德对慢性阻塞性肺疾病急性加重(AECOPD)合并Ⅱ型呼吸衰竭患者APACHEⅡ评分及机械通气的影响。方法将我院收治的56例AECOPD合并Ⅱ型呼吸衰竭患者依据治疗方案分为试验组(n=28,BiPAP无创呼吸机联合经管道雾化吸入布地奈德治疗)和参照组(n=28,BiPAP无创呼吸机治疗)。比较两组患者的治疗效果。结果治疗后,试验组的FEV1、FVC均高于治疗前和参照组,APACHEⅡ评分均显著低于治疗前和参照组(P<0.05)。试验组呼吸困难改善时间、机械通气时间及住院时间均显著短于参照组(P<0.05)。结论AECOPD合并Ⅱ型呼吸衰竭患者采取BiPAP无创呼吸机联合经管道雾化吸入布地奈德治疗,能改善肺功能及APACHEⅡ评分,加快康复进程。
Objective To analyze the influences of bi-level positive airway pressure(BiPAP) non-invasive ventilator combined with budesonide inhalation via pipeline on APACHEⅡ score and mechanical ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD) with type Ⅱ respiratory failure. Methods Fifty-six patients with AECOPD and type Ⅱ respiratory failure treated in our hospital were divided into experimental group(n=28,BiPAP non-invasive ventilator combined with budesonide inhalation via pipeline) and reference group(n=28, BiPAP noninvasive ventilator) according to the treatment plan. The therapeutic effects of the two groups were compared. Results After treatment, FEV1 and FVC in the experimental group were higher than those before treatment and in the reference group,and APACHE Ⅱ score were significantly lower than that before treatment and in the reference group(P <0.05). The improvement time of dyspnea, mechanical ventilation time and hospitalization time of the experimental group were significantly shorter than those of the reference group(P <0.05). Conclusion For patients with AECOPD with type Ⅱrespiratory failure, BiPAP non-invasive ventilator combined with budesonide inhalation via pipeline can improve the pulmonary function and APACHEⅡ score, and accelerate the rehabilitation process.
作者
周华锋
裴辉
全阳
李广志
ZHOU Hua-feng;PEI Hui;QUAN Yang;LI Guang-zhi(Intensive Care Unit,Zhengzhou Yihe Hospital,Zhengzhou 450000;Emergency Intensive Care Unit,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《临床医学研究与实践》
2020年第4期44-45,共2页
Clinical Research and Practice
