摘要
目的探讨血清Hcy,ABCD3-I评分及经颅多普勒对短暂性脑缺血发作后7d内继发脑梗死的预测价值。方法分析2018年9月~2019年5月我院收治的短暂性脑缺血发作患者62例,收集62例患者影像学、临床资料等,采用ABCD3-I评分法将患者分为低危组(16例)、中危组(34例)、高危组(12例)。记录患者血清Hcy及经颅多普勒资料,计算患者7d内脑梗死的发生率。结果血清Hcy水平越高,7d内发生脑梗死的概率越大。与<10μmol/L组相比,其余两组差异有显著性(P<0.05),与~15μmol/L组相比,血清Hcy升高组差异有显著性(P<0.01);低危组7d内脑梗死发生率为12.50%,中危组26.47%,高危组58.33%,高危组7d内脑梗死发生率明显高于低危组、中危组,差异有显著性(P<0.05);正常或轻度、中度、重度脑供血动脉狭窄程度组7d内脑梗死发生率分别为4.17%,9.52%,58.82%,重度狭窄组7d内脑梗死发生率明显高于正常或轻度、中度狭窄组,差异有显著性(P<0.05)。结论血清Hcy,ABCD3-I评分结合经颅多普勒可有效提高预测短暂性脑缺血发作后7d内继发脑梗死的准确度。
Objective To explore the predictive value of serum Hcy,ABCD3-I score and transcranial Doppler in secondary cerebral infarction within 7 days after transient ischemic attack(TIA).Methods Sixty-two patients with TIA admitted to our hospital from September 2018 to May 2019 were enrolled and their imaging and clinical data were collected.The patients were divided into low-risk group(16 cases),middle-risk group(34 cases) and high-risk group(12 cases) by ABCD3-I scoring method.The data of serum Hcy and transcranial Doppler were recorded and the incidence of cerebral infarction within 7 days was calculated.Results The higher the level of serum Hcy,the higher the probability of cerebral infarction within 7 days.Compared with the <10μmol/L group,the difference between the other two groups is significant(P<0.05).Compared with the ~15μmol/L group,the serum Hcy increased group has significant difference(P<0.01).The incidence of cerebral infarction in the low-risk group was 12.50%,26.47% in the medium-risk group,58.33% in the high-risk group and the incidence of cerebral infarction in the high-risk group in 7 days was significantly higher than the low-risk group and the middle-risk group,which has significant difference(P<0.05).The incidence of cerebral infarction within 7 days of normal or mild,moderate and high cerebral artery stenosis was 4.17%,9.52% and 58.82%,respectively.The incidence of cerebral infarction within 7 days of high cerebral stenosis was significantly higher than that of normal or mild or moderate cerebral artery stenosis(P<0.05).Conclusion Serum Hcy,ABCD3-I score combined with transcranial Doppler can effectively improve the accuracy of predicting secondary cerebral infarction within 7 days after TIA.
作者
赵敏
王秀锦
刘振兴
耿建红
ZHAO Min;WANG Xiujin;LIU Zhenxing;GENG Jianhong(Department of Neurology,Weifang Medical University,Weifang 261053,China;Department of Neurology,the Affiliated Hospital of Weifang Medical University)
出处
《潍坊医学院学报》
2019年第6期407-410,共4页
Acta Academiae Medicinae Weifang
