摘要
研究了快速溶剂萃取-液相色谱/质谱联用技术测定血液中PFAAs的方法。血液样品经过冷冻干燥,利用加速溶剂萃取的方法,最后使用液相色谱-质谱仪分析检测PFAAs成分。方法的回收率为74.6%~128.8%,检出限为1.10~25.1 ng/L。通过对珠江三角洲地区人群血液样本的分析,发现∑9PFAAs的浓度为26.8~557 ng/g,平均值为176±90.1 ng/g。血液中PFAAs的主要成分以PFHxA和PFOS为主,分别占血液中PFAAs浓度的20.97%和66.98%。人群血液中最常见和浓度最高的PFAAs是PFOS,而PFOA浓度相对较低。
A method for the determination of perfluorinated compounds(PFAAs)in blood by accelerated solvent extraction(ASE)coupled with liquid chromatography-mass spectrometry(LC-MS)was established.After freezedrying,samples were extracted by accelerated solvent extraction.Finally,PFAAs were analyzed by LC-MS.The recoveries were 74.6%-128.8%and the detection limits were 1.10-25.1 ng/L,respectively.Based on the analysis of blood samples from the population in the Pearl River Delta,it was found that the concentration of 9 PFAAs was 26.8-557 ng/g,with an average of 176±90.1 ng/g.PFAAs in blood were mainly PFHxA and PFOS,accounting for 20.97%and 66.98%of the concentration of PFAAs in blood,respectively.The most common and highest concentration of PFAAs in human blood is PFOS,while the concentration of PFOA is relatively low.
作者
宋小飞
施召才
马伟文
银玉容
史伟
SONG Xiaofei;SHI Zhaocai;MA Weiwen;YIN Yurong;SHI Wei(School of Environment and Energy,South China University of Technology,Guangzhou 510006)
出处
《分析试验室》
CAS
CSCD
北大核心
2020年第1期53-56,共4页
Chinese Journal of Analysis Laboratory
基金
广东省自然科学基金(B6160760)资助
关键词
快速溶剂萃取
液相色谱-质谱
全氟化合物
accelerated solvent extraction
liquid chromatography-mass spectrometry
perfluorinated compounds
