摘要
目的研究胆囊切除术后综合征(PCS)患者中医证候规律。方法2014年3月~2018年3月我院诊治的50例PCS患者,记录42个中医症候,应用因子-聚类分析法对PCS患者临床症状进行分析,探讨其中医证候分布规律。结果在50例PCS患者,以恶心呕吐(68.0%)、胁肋窜痛(66.0%)、胁肋胀痛(48.0%)、胸脘胀满(32.0%)、精神倦怠(48.0%)、乏力(44.0%)、头重身重(44.0%)、纳差(40.0%)、便溏(26.0%)和不思饮食(52.0%)为主要症状表现;经KMO检验,KMO=0.8,经Bartlett检验,近似卡方值为13454.5(P<0.05);因子分析发现12个公因子,按照病位和证素,将PCS分为6个证型,依次为肝气郁结型(42.0%)、肝胆湿热型(20.0%)、脾虚胃弱型(18.0%)、寒凝阳衰型(10.0%)、胆扰心神型(6.0%)和血瘀气滞型(4.0%)。结论PCS患者中医症状分散性良好,证候较为明确,其中以肝气郁结、肝胆湿热和脾虚胃弱为主,或许可以指导临床诊治。
Objective The purpose of this study was to investigate the traditional Chinese medicine(TCM)syndrome of post-cholecystectomy syndrome(PCS)based on factor-cluster analysis.Methods The clinical data mainly including TCM syndrome in 50 patients with PCS were collected in our hospital between March 2014 and March 2018.The PCS symptom were analyzed by factor-cluster analysis.Results The main TCM syndromes in our series were as follows,e.g.nausea and vomiting accounted for 68.0%,hypochondriac and running pain for 66.0%,costal channeling pain for 48.0%,chest swelling for 32.0%,mental burnout for 48.0%,fatigue for 44.0%,poor appetite for 40.0%and loose stool for 26.0%;the KMO test showed that the KMO was 0.8,and the Bartlett test showed that the approximate chi-square value was 13454.5(P<0.05);the factor analysis showed that there were 12 common factors,and the patients with PCS were classified into six syndrome types based on disease location and syndrome elements;the six syndromes were stagnation of Liver-qi in 42.0%,the dampness-heat of liver and gallbladder in 20.0%,the spleen-deficiency and stomach-weakness in 18.0%,the cold-congealing and yang-failure in 10.0%,the disturbance of heart and mind in 6.0%,and the blood stasis-qi stagnation in 4.0%.Conclusion The results of factor-cluster analysis showed that the TCM symptoms of patients with PCS were well dispersed and the syndromes were clear.The main symptoms were stagnation of liver-qi,dampness-heat of liver-gallbladder and weakness of spleen and stomach,which might help clinicians to manage the patients with PCS.
作者
漆若毅
李洋
Qi Ruoyi;Li Yang(Department of Gastroenterology,Shaanxi University of Traditional Chinese Medicine.Xianyang 719000,Shaanxi Province,China)
出处
《实用肝脏病杂志》
CAS
2020年第1期126-129,共4页
Journal of Practical Hepatology
基金
陕西省自然科学基础研究计划项目(编号:2017JQ3030)
关键词
胆囊切除术后综合征
中医证候
因子分析
聚类分析
Post-cholecystectomy syndrome
TCM syndromes
Factor analysis
Cluster analysis
