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正常成年人嗅球体积测量的MR研究 被引量:1

Magnetic resonance imaging study on olfactory bulb volume in normal adults
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摘要 目的探讨成年人嗅球的MR扫描及体积测量方法,初步建立正常成年人嗅球的体积范围。方法将82例健康志愿者按年龄分成4组,将20岁组和30岁组称为青年组,50岁组和60岁组称为老年组,采用MR T1 IR序列扫描,应用计算机辅助的体积分析法计算双侧嗅球体积,了解嗅球体积随年龄变化的关系,比较双侧及两性之间嗅球体积差异。结果青年组与老年组男性嗅球体积经比较差异具有统计学意义(P=0.048);60岁组两性间嗅球体积经比较差异具有统计学意义(P=0.03);各年龄组两侧嗅球体积差异无统计学意义(P>0.05)。结论 MR T1 IR序列能清晰的显示嗅球轮廓,可用于嗅球的体积测量研究。随年龄的增长,男性嗅球体积逐渐减小;不同于男性,女性嗅球缩小幅度较小,且在老年组体积略有增大;各年龄组嗅球体积侧别之间无差异。 Objective To investigate the methods of magnetic resonance(MR) scanning and volume measurement of olfactory bulb and establish the volume range of olfactory bulb in normal adults.Methods Eighty-two healthy volunteers were divided into four groups according to age. MR T1 IR sequence scanning was adopted to scan bilateral olfactory bulb, and the volumes of bilateral olfactory bulb were calculated by computer aided volume analysis method. The correlation between gender and olfactory bulb volume and the tendency of olfactory bulb volume on different age groups were studied.Results There was a difference in olfactory bulb volume between the young male group and the old male group(P=0.048). There was a gender difference between olfactory bulb volume in the 60-year-old group(P=0.03),There is no significant difference in olfactory bulb volume between the two sides(P>0.05).Conclusion MR T1 IR sequence can clearly show the olfactory bulb contour and can be used for the measurement of olfactory bulb volume. The olfactory bulb volume shows tendency to decrease with age in male. On the contrary, the olfactory bulb in female shrinks less than in male and increases slightly in the elderly.There is no significant difference between the two sides.
作者 孟岩 邢园 龚龙岗 麻少辉 郭晨光 MENG Yan;XING Yuan;GONG Long-gang;MA Shao-hui;GUO Chen-guang(Department of Otolaryngology Head and Neck Surgery,Honghui Hospital,Xi’an Jiaotong University,Xi’an 710054,China;Department of Medical Imaging,the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,China)
出处 《中国耳鼻咽喉颅底外科杂志》 CAS 2020年第1期53-57,共5页 Chinese Journal of Otorhinolaryngology-skull Base Surgery
关键词 嗅球 体积测量 磁共振 Magnetic resonance Olfactory bulb Volumetric measurement
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