摘要
单纯疱疹病毒1型(herpes simplex virus type 1,HSV-1)通常引起口唇疱疹,但近年来其引发的生殖道疱疹亦越来越多,且与阿尔茨海默病的发生密切相关。HSV-1和HSV-2已经成为全球感染率最高的性传播疾病之一,并显著增加罹患艾滋病及其他生殖道疾病的风险,这些新的流行病学资料改变了过去对HSV的忽视,促使各个国家迫切开始重视针对HSV感染情况的数据收集和开发新的疫苗设计策略。基于全球对HSV感染的新认识和举措,本文将从不同角度分别对世界和国内HSV流行情况作一综述,以期了解HSV近年的感染趋势和传播特点。
Herpes simplex virus type 1(HSV-1)commonly causes orolabial ulcers.However,HSV-1 has become an increasing cause of genital infection in recent years and found to have close relationship associated with Alzheimer′s disease.HSV infection is one of the most common sexually transmitted diseases.It has been received renewed attention in recent years,due to improvements in the understanding of the epidemiological synergy between HSV and other severe diseases,including HIV,sexually transmitted infections,and even neurocognitive impairment.In the context of global renewed attention and responses to HSV infection,we summarize the epidemic of HSV infection at home and abroad in this review,to provide an overview of the data available on HSV infections situation,trends and responses.
作者
冯敏
高杨
杨亚丽
李琦涵
Feng Min;Gao Yang;Yang Yali;Li Qihan(Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases,Institute of Medical Biology,Chinese Academy of Medical Sciences&Peking Union Medical College,Kunming 650118,China;Department of Pathology,the Second People′s Hospital of Yunnan Province,Kunming 650021,China)
出处
《中华微生物学和免疫学杂志》
CAS
CSCD
北大核心
2019年第12期937-950,共14页
Chinese Journal of Microbiology and Immunology
基金
云南省科学技术厅重大科技专项项目(2017ZF006)
中国医学科学院医学与健康科技创新工程重大协同创新项目(2016-I2M-1-019)。
关键词
单纯疱疹病毒
诊断和检测方法
流行病学分析
Herpes simplex virus
Diagnosis and detection methods
Epidemiological analysis
