摘要
目的:观察壮药"膝痹外洗方"结合"膝舒方"治疗膝骨关节炎("骆芡病")的临床疗效。方法:将120例膝骨关节炎患者随机分为A、B、C、D组,每组30例;A组患者予"膝舒方"内服,B组患者予"膝痹外洗方"外洗患膝,C组患者予"膝舒方"内服结合"膝痹外洗方"外洗;D组患者予依托考昔口服。分别于治疗前、治疗2周后进行VAS评分及Lequesne指数评分,并评价临床疗效。结果:4组患者治疗2周后膝关节VAS评分及Lequesne指数评分均降低,差异有统计学意义(P<0.05);C组患者治疗后膝关节VAS评分及Lequesne指数评分低于A、B、D组,差异有统计学意义(P<0.05);C组总有效率高于A、B、D组,差异有统计学意义(P<0.05)。结论:"膝痹外洗方"结合"膝舒方"治疗膝骨关节炎有较好疗效,能改善患者临床症状体征,缓解疼痛。
Objective: To observe the clinical effect of the Zhuang medicine "Xibi-Waixifang" combined with "Xishu-Fang" in the treatment of "Luo Qian" disease(knee osteoarthritis). Methods: Totally 120 patients with knee osteoarthritis were randomly divided into four groups, group A, B, C and D, 30 cases in each group;Group A was given "Xishu-Fang" orally;Group B was given "Xibi-Waixifang" external washing of the affected knee;Group C was given "Xishu-Fang" orally and "Xibi-Waixifang" external washing;Group D was given Etocoxib. VAS score and Lequesne index score were performed before treatment and two weeks after treatment,and the clinical efficacy was compared. Results: The VAS scores and Lequesne index scores decreased in the four groups after treatment for 2 weeks(P<0.05), and group C showed lower VAS score and Lequesne index score than group A, B and D(P<0.05). Group C showed higher total effitive rate than group A, B and D(P<0.05). Conclusion: The combination of "Xibi-Waixifang" and "Xishu-Fang" showed good effect on the treatment of knee osteoarthritis, which can improve the clinical symptoms and signs and relieve pain.
作者
黄肖华
冯英华
周祥兴
江文勇
李财云
柯辉雄
黄杰
闫连杰
HUANG Xiao-hua;FENG Ying-hua;ZHOU Xiang-xing;JIANG Wen-yong;LI Cai-yun;KE Hui-xiong;HUANG jie;YAN Lian-jie(The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning Guangxi 530023,China;Guangxi University of Traditional Chinese Medicine,Nanning Guangxi 530001,China)
出处
《中医药导报》
2019年第23期61-63,73,共4页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
广西卫计委立项课题（Z2016664）
关键词
壮药
膝痹外洗方
膝舒方
膝骨关节炎
骆芡病
Zhuang medicine
Xibi-Waixifang
Xishu-Fang
knee osteoarthritis
Luo Qian disease
