急性ST段抬高型心肌梗死的梗死相关动脉自发再通的预测因素分析被引量：5

Predictive factors analysis of spontaneous recanalization of arteries associated with acute ST-segment elevation myocardial infarction

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摘要目的研究急性ST段抬高型心肌梗死(ST segment elevation myocardial infarction,STEMI)梗死相关动脉(infarction related artery,IRA)自发再通(spontaneous recanalization,SR)的预测因素。方法选择符合条件的2018年1〜12月就诊于西安交通大学第一附属医院的STEMI患者共287例,根据冠状动脉造影结果分为SR组(TIMI血流2〜3级)和非SR组(TIMI血流0〜1级),观察两组一般临床资料及生化指标等,应用Logisitic多因素回归分析评价发生SR的预测指标c结果与非SR组相比较,SR组中梗死前心绞痛检出率更高(41.7%比18.7%,P<0.05),单核细胞计数、随机血糖、入院即刻肌酸激酶同工酶(CK-MB)值和脂蛋白(a)Lp(a)更低[(0.56±0.15)xl09比(0.74±0.14)x 109,(7.45±1.88)mmol/L比(9.92±2.01)mmol/L,(68.08土22.24)U/L比(79.20±26.09)U/L,(143.06±60.57)nmol/L比(192.03±65.87)nmol/L,P<0.05],两组其余各项指标比较差异无统计学意义(P>0.05)o多因素Logisitic回归分析显示,梗死前心绞痛、单核细胞计数和Lp(a)与STEMI患者发生SR有较好的相关性。结论梗死前心绞痛、单核细胞计数和Lp(a)可以作为STEMI患者发生SR的预测因素。 Objective Study on the predictors of spontaneous recanalization(SR)of infarction related artery(IRA)in patients with acute ST-elevation myocardial infarction(STEMI).Methods A total of 287 patients with acute STEMI who met the criteria were enrolled.According to the results of coronary angiography,they were divided into SR group(TIMI blood flow 2-3)and non-SR group(TIMI blood flow 0-1).The general clinical data and biochemical indicators were observed and used the Logisitic regression analysis to evaluate the predictive index of SR.Results Compared with the non-SR group,the pre-infarction angina was more detected in the SR group(41.7%vs 18.7%,P<0.05),monocyte count,random blood glucose,immediate creatine kinase isoenzyme(CK-MB)and lipoprotein(α)[Lp(α)]were lower than non-SR group[(0.56±0.15 vs 0.74±0.14)×109,(7.45±1.88 vs 9.92±2.01)mmol/L,(68.08±22.24 vs 79.20±26.09)U/L,(143.06±60.57 vs 192.03±65.87)nmol/L,P<0.05].There were no significant differences in the remaining indicators between the two groups(P>0.05).Logisitic multiple factors Regression analysis showed that pre-infarction angina,monocyte count,Lp(α)had a good correlation with SR in STEMI patients.Conclusion Preinfarction angina pectoris,monocyte count and Lp(α)can be used as predictors of SR in patients with acute STEMI.

作者马云龙刘平吴岳田刚李红兵 MA yun-long;LIU ping;WU Yue;TIAN Gang;LI Hong-bing(Department of Cardiology,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)

机构地区西安交通大学第一附属医院心血管内科

出处《中国心血管病研究》 CAS 2020年第1期82-85,共4页 Chinese Journal of Cardiovascular Research

关键词急性ST段抬高型心肌梗死自发再通预测因素 Acute St segment elevation myocardial infarction Spontaneous recanalization Predictors

分类号 R542.22 [医药卫生—心血管疾病]

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