摘要
目的分析腹腔镜手术患者使用七氟烷或异丙酚复合瑞芬太尼进行麻醉价值。方法选择2016年12月~2018年12月进行腹腔镜手术的100例患者为研究样本,采取随机数字排列表法将其分成每组50例的常规组以及试验组,予以常规组瑞芬太尼以及异丙酚进行麻醉,予以试验组瑞芬太尼以及七氟烷进行麻醉。比较两组麻醉前后心率、平均动脉压水平;麻醉各时期血浆一氧化氮水平、内皮素-1水平。结果麻醉后试验组在心率、平均动脉压方面水平均低于常规组,差异有统计学意义(P<0.05)。气腹建立后15 min试验组血浆一氧化氮水平高于常规组,内皮素-1水平低于常规组,差异有统计学意义(P<0.05)。结论相较于异丙酚复合瑞芬太尼,七氟烷与瑞芬太尼联合使用可维持腹腔镜手术患者机体血流动力学指标平稳,麻醉效果满意。
Objective To analyze the anesthesia effect of Sevoflurane or Propofol combined with Remifentanil during laparoscopic surgery.Methods 100 patients underwent laparoscopic surgery(2016.12~2018.12)were chosen as research samples.According to random number table,patients were assigned to routine group(n=50)and test group(n=50).The routine group was treated with Remifentanil and Propofol;the test group was treated withRemifentanil and Sevoflurane.Heart rate and mean arterial pressure as well as plasma nitric oxide and endothelin-1 contents during surgery were compared.Results After anesthesia,heart rate and mean arterial pressure in the test group were significantly lower than routine group(P<0.05);after 15min of pneumoperitoneum,plasma nitric oxide contents in the test group were higher than routine group;endothelin-1 contents were significantlylower than routine group(P<0.05).Conclusion The combined anesthesia of Sevoflurane and Remifentanil can maintain the stable hemodynamic indicators and increase the anesthesia effect.It shall be widely applied in clinical practice.
作者
邱海艳
孙亚玲
李锋
QIU Hai-yan;SUN Ya-ling;LI Feng(Department of Anesthesiology,Yancheng First People's Hospital,Yancheng,Jiangsu 224000,China.)
出处
《中国处方药》
2020年第1期63-64,共2页
Journal of China Prescription Drug
关键词
腹腔镜
瑞芬太尼
异丙酚
七氟烷
Laparoscopic surgery
Remifentanil
Propofol
Sevoflurane
