摘要
目的安徽省肿瘤登记工作起步较晚,目前对食管癌发病和死亡的分析资料较少,本研究通过分析安徽省2010-2015年食管癌发病和死亡趋势变化情况,为制定安徽省食管癌防治措施提供基础数据。方法将安徽省2010-2015年各肿瘤登记处上报数据按照地区(城乡)、性别分层计算食管癌发病率和死亡率,采用2000年中国标准人口构成分别计算中国人口标化发病/死亡率,进行发病率和死亡率的年度趋势分析。结果 2010-2015年安徽省食管癌发病粗率为28.23/10万,中标率为21.20/10万;城市地区食管癌发病粗率为20.17/10万,中标率为14.71/10万;农村地区食管癌发病粗率为35.62/10万,中标率为27.40/10万。2010-2015年安徽省食管癌死亡粗率为18.90/10万,中标率为13.84/10万;城市地区食管癌死亡粗率为14.59/10万,中标率为10.38/10万;农村地区食管癌发病粗率为22.86/10万,中标率为17.16/10万。安徽省食管癌发病率2010-2015年度有下降趋势(APC=-0.32%,P>0.05),但在不同组别差异均无统计学意义;城市组发病率呈现下降趋势(APC=-5.57%,P<0.05),其中城市女性(APC=-6.35%,P<0.05)和男性有下降趋势(APC=-5.17%,P>0.05),但男性差异无统计学意义;农村组发病率呈现上升趋势,但是在各个组别差异均无统计学意义。安徽省食管癌死亡率2010-2015年度呈现上升趋势,差异有统计学意义(APC=5.16%,P<0.05),男性(APC=4.78%,P<0.05)和女性组(APC=6.39%,P<0.05)均上升;城市地区各个组别死亡率呈现下降趋势,但差异均无统计学意义;农村组死亡率呈现上升趋势,在女性组(APC=9.77%,P<0.05)差异有统计学意义。结论安徽省近年来城市地区食管癌发病率和死亡率均有下降趋势,农村地区食管癌发病率变化不大而死亡率有上升趋势,必须加强农村地区防治工作,推进上消化道癌症早诊早治工作,降低食管癌的发病率和死亡率,提高食管癌5年生存率。
OBJECTIVE Anhui started cancer registration in a short time,and data of esophageal cancer in Anhui is few.This paper analyzed the esophageal cancer incidence and mortality in Anhui province from 2010 to 2015,in order to provide basic data for making policy for preventing esophageal cancer.METHODS Reported registries’ data was qualified after data assessment as pooled data from 2010 to 2015.Cancer incidence and mortality were stratified by gender and regions.Crude incidence rate and crude mortality rate were calculated.Population census in China 2000 was used for agestandardized incidence/mortality,trends of incidence and mortality from 2010 to 2015 was calculated by joinpoint software.RESULTS The crude incidence rate of esophageal cancer in all areas was 28.23/100 000,with age-standardized rate by Chinese standard population of 21.10/100 000.The crude incidence rate of esophageal cancer in urban areas was20.17/100 000,with age-standardized rate by Chinese standard population of 14.71/100 000.The crude incidence rate of esophageal cancer in rural areas was 35.62/100 000,with age-standardized rate by Chinese standard population of 27.40/100 000.The crude mortality rate of esophageal cancer in all areas was 18.90/100 000,with age-standardized rate by Chinese standard population of 13.84/100 000.The crude mortality rate of esophageal cancer in urban areas was 14.59/100 000,with age-standardized rate by Chinese standard population of 10.38/100 000.The crude mortality rate of esophageal cancer in rural areas was 22.86/100 000,with age-standardized rate by Chinese standard population of 17.16/100 000.The incidence of esophageal cancer from 2010-2015 in all groups show a decline trend(APC=-0.32%,P>0.05),but without statistical differences in all groups.The incidence of esophageal cancer in urban groups show a decline trend(APC=-5.17%,P<0.05),with statistical differences,decline trend was shown in urban female group(APC=-6.35%,P<0.05)and male group(APC=-5.17%,P>0.05).The incidence of esophageal cancer in rural groups showed an increase trends without statistical differences.The mortality of esophageal cancer from 2010-2015 in all groups showed an increase trend(APC=5.16%,P<0.05),in male group(APC=4.78%,P<0.05)and female group(APC=6.39%,P<0.05).The mortality of esophageal cancer in urban group showed a decline trend,but without statistical differences in all groups.The mortality of esophageal cancer in rural group showed an increase trend and with statistical differences in female group(APC=9.77%,P<0.05).CONCLUSIONS The incidence and mortality in urban areas showed a decrease trends.The incidence in rural areas did not show any change while the mortality in rural areas showed an increase trends.The rural population should be focused on,the prevention and control of esophageal cancer should be enhanced,early diagnosis and treatment of esophageal cancer needs to be promoted,to reduce the morbidity and mortality caused by esophageal cancer.
作者
戴丹
贾尚春
徐伟
陈叶纪
查震球
刘志荣
DAI Dan;JIA Shang-chun;XU Wei;CHEN Ye-ji;ZHA Zheng-qiu;LIU Zhi-rong(Department of Chronic Disease,Center for Disease Control and Prevention of Anhui Province,Hefei 230601,P.R.China)
出处
《中华肿瘤防治杂志》
CAS
北大核心
2019年第22期1663-1668,共6页
Chinese Journal of Cancer Prevention and Treatment
基金
国家重点研发计划(2016YFC1302800
2016YFC0901400)
2017年度安徽省重点研究与开发计划(1704a0802156)
关键词
食管癌
肿瘤登记
发病率
死亡率
安徽省
esophageal cancer
cancer registry
incidence
mortality
Anhui Province
